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- W2394373833 abstract "OBJECTIVE To explore the clinical predisposing factors and fungal drug resistance of ICU central venous catheter-related bloodstream fungal infections,in order to improve the clinical diagnosis and treatment.METHODS A retrospective analysis was conducted for 65 patients with ICU central venous catheter-related bloodstream infections from Jan.2010-Jan.2013 and risk factors for fungal infections and drug resistance of pathogens were analyzed.RESULTS Totally there were 13 cases of ICU central venous catheter-related bloodstream fungal infections,the infection rate was 35.38%.A total of 39 strains were isolated,among which Candida tropicalis was the most predominant,accounting for 33.33%.C.tropicalis and Candida parapsilosis had low resistance to amphotericin B,being 7.69%and 11.11%.Candida albicans had a low resistance of 10.0%to flucytosine,Candida glabrata had 0%resistance to ketoconazole.Risk factors for ICU central venous catheter-related bloodstream fungal infection included central venous catheter for a long time( 14d),hypoalbuminemia,multiple venous catheter connectors(3),aplurality of indwelling body cavity drainage(4),the combination use of antibiotics for a long time(7d),accompanying by infection in other sites,parenteral nutrition for a long time( 7d),and a serious condition(score of 4-5points)(P0.05).CONCLUSIONICU central venous catheter-related bloodstream infection is closely related to factor such as catheter time.Enhanced intervention can reduce the incidence of infections." @default.
- W2394373833 created "2016-06-24" @default.
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- W2394373833 date "2014-01-01" @default.
- W2394373833 modified "2023-09-28" @default.
- W2394373833 title "Clinical specific diagnosis and treatment of ICU central venous catheter-related bloodstream fungal infections" @default.
- W2394373833 hasPublicationYear "2014" @default.
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