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- W2394399532 abstract "Objective:To observe the therapeutic effects of Polyrhachis vicina Roger on gout.Method:Kunming mice and Wistar rats were randomly divided into control group,model group,positive control group,P.vicina low,medium and high dose groups(1,2,4 g·kg-1),respectively.The anti-gout effects of P.vicina were studied by observing its effects on the level of blood uric acid in hyperuricacidemia mice induced by hypoxanthine and nomal mice,and rat's foot swelling induced by microcrystalline sodium urate(MSU) after 15 days treatment.Result:Compared to the level of blood uric acid in control group(131.09±45.78) μmol·L-1and model group(198.63±47.27)μmol · L-1,medium(2 g · kg-1) and high dose groups(4 g · kg-1)of P.vicina alcohol extract,and high dose group(4 g · kg-1)water extract could reduce the blood uric acid in model mice,and satisfactory inhibited acute gouty arthritis,relieved rat's foot welling in model rats induced by MSU in 3 hours.The effects of P.vicina alcohol extract on gout was better than that in water extract.Conclusion:P.vicina could inhibit the level of blood uric acid in hyperuricacidemia mice induced by hypoxanthine and inflammation induced by MSU,which indicates that P.vicina has therapeutic effect on gout." @default.
- W2394399532 created "2016-06-24" @default.
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- W2394399532 date "2012-01-01" @default.
- W2394399532 modified "2023-10-01" @default.
- W2394399532 title "Empirical Study of Polyrhachis vicina in Treatment of Gout" @default.
- W2394399532 hasPublicationYear "2012" @default.
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