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- W2394418805 abstract "Objective To study the clinical features, sensitization drugs and prognosis related factors of patients with severe drug eruption. Methods The clinical data of 23 patients with severe drug eruption in the First People's Hospital of Huzhou City from March to August 2013 were retrospectively analyzed, including main disease types and sensitization drugs. At the same time the patients were divided into different groups respectively according to the disease types and sensitization drugs, and their clinical therapeutic effects were summarized. Factors associated with prognosis were analyzed. Results Among 23 patients with severe drug eruption, 15 cases(65.21%) had severe erythema multiforme type drug eruption, 9 patients(39.14%) had sensitization induced by Penicillin and Cephalosporin, they were the highest incidence of disease types and sensitization drugs. The treatment effect of patients with different disease types and sensitization drugs had no statistically significant difference(P 0.05). Age, treatment time, the degree of visceral involvement, routine blood leukocytes, fasting glucose, albumin, aspertate aminotransferase(AST), alanine aminotransferase(ALT) were the factors associated with prognosis(P 0.05). Conclusion Severe erythema multiforme type drug eruption is the primary type of severe drug eruption, and Penicillin and Cephalosporin are the main sensitization drugs. Age, treatment time, the degree of visceral involvement, routine blood leukocytes, fasting glucose, albumin, AST, ALT are related to prognosis." @default.
- W2394418805 created "2016-06-24" @default.
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- W2394418805 date "2014-01-01" @default.
- W2394418805 modified "2023-09-24" @default.
- W2394418805 title "Retrospective analysis of clinical features, sensitization drugs and prognosis related factors of severe drug eruption" @default.
- W2394418805 hasPublicationYear "2014" @default.
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