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- W2394450016 abstract "OBJECTIVE: To study pharmacokinetics and relative bioavailability following oral administration of loxoprofen sodium tablet in healthy volunteers. METHODS: A single oral domestic and imported loxoprofen tablets were given according to a randomized 2 way cross-over design. Plasma concentration of loxoprofen was determined by HPLC. RESULTS: The main pharmacokinetic parameters after oral administration of domestic and imported loxoprofen sodium tablet(60mg) were: t1/2ke 93. 9 ± 19.8min, 92.4± 16.3min; AUC0-t 596.97 ± 104.l2μg.min.mL-1,598.18 ± 109.62μg. min.mL-1; Cmax 6.40 ± 2.12μg.mL-1 , 6.60 ± 2.04μg.mL-1,tmax 25.0± 14.3min,23. 5 ± 10.3min, respectively. CONCLUSION: The relative bioavailability of domestic loxoprofen sodium tablet was(101.2 ± 17.4)%. The results demonstrated that two formations of loxoprofen sodium tablet were bioequivalent." @default.
- W2394450016 created "2016-06-24" @default.
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- W2394450016 date "2003-01-01" @default.
- W2394450016 modified "2023-09-27" @default.
- W2394450016 title "Ralative Bioavailability of Loxoprofen Sodium Tablet in Healthy Volunteers" @default.
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