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- W2394456293 abstract "Objective:To evaluate the hepatic and renal damage of bushenyigugao in rats and the reversibility of these damage. Method:144 rats were divided randomly into three groups. 44 rats in control group received distilled water; 50 rats in high-dose group received 60.0 g·kg -1 intragastric administration per day; 50 rats received 15.0 g·kg -1 intragastric administration per day. After 90 day's , 180 day's administration and in the 30th day after 180 day's administration, the level of aspartate aminotransferase (AST), albumin aminotransferase (ALT), alkaline phophatase (ALP), blood urea nitrogen (BUN), creatinine (Cr) in the serum was detected, meanwhile liver and renal pathology was examinated by light microscopy. Results:Long-term bushenyigugao using may lead to renal damage and reversible low-grade liver damage. Conclusion:The hepatic and renal function tests should be performed periodly with long-term high-dose bushenyigugao using." @default.
- W2394456293 created "2016-06-24" @default.
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- W2394456293 date "2003-01-01" @default.
- W2394456293 modified "2023-09-23" @default.
- W2394456293 title "The Hapertic and Renal Damage of Bushenyigugao in Rats" @default.
- W2394456293 hasPublicationYear "2003" @default.
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