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- W2394459239 abstract "ve To evaluate the usefulness of measuringα-fetoprotein(AFP)variants as a prognostic marker for patients withhepatocellular carcinoma(HCC).Methods Serum AFP variantlevels were measured by crossed immunoaffino-electrophoresis in thepresence of lectin(Pisum Sativum agglutinin)before initial surgicaltreatment in 129 HCC patients.AFP variant was calculated as the ratio of lectin reactive AFP to total AFP multiplied by 100.Recurrence and survival were compared between patients with AFP variant level≥20 % (Group A, n = 83)and patients with AFPvariant level 20% (Group B, n = 46). Results The recurrencerates for all patients after 1, 3, and 5 yr were 32.6% (42/l29),66.7% (86/129), and 86.8% (ll2/l29) respectively.The overallrecurrence rate was significantly higher in Group A than in Group B.The survival rates for all patients afterl, 3, and 5 yr were 88.4%(ll4/l29), 63.6% (82/129), and 41.l % (53/129 ),respectively.Survival time was significatly longer in Group B than in Group A.Conclusion Measurement of AFP variants may be a good indicatorof biological malignancy and an useful marker for predictingrecurrence and outcome in HCC." @default.
- W2394459239 created "2016-06-24" @default.
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- W2394459239 date "2001-01-01" @default.
- W2394459239 modified "2023-09-26" @default.
- W2394459239 title "PISUM SATIVUM AGGLUTINIS REACTVE-α-FETOPROTEIN AS A SIGNIFICANT MARKER OF POORPROGNOSIS FOR HEPATOCELLULAR CARCINOMA" @default.
- W2394459239 hasPublicationYear "2001" @default.
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