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- W2394642790 endingPage "37" @default.
- W2394642790 startingPage "13" @default.
- W2394642790 abstract "Cancer is one of the major and leading causes of death worldwide. Two of the greatest challenges in fighting cancer are early detection and effective treatments with no or minimum side effects. Widespread use of targeted therapies and molecular imaging in clinics requires high affinity, tumor-specific agents as effective targeting vehicles to deliver therapeutics and imaging probes to the primary or metastatic tumor sites. Combinatorial libraries such as phage-display and one-bead one-compound (OBOC) peptide libraries are powerful approaches in discovering tumor-targeting peptides. This review gives an overview of different combinatorial library technologies that have been used for the discovery of tumor-targeting peptides. Examples of tumor-targeting peptides identified from each combinatorial library method will be discussed. Published tumor-targeting peptide ligands and their applications will also be summarized by the combinatorial library methods and their corresponding binding receptors." @default.
- W2394642790 created "2016-06-24" @default.
- W2394642790 creator A5002480954 @default.
- W2394642790 creator A5016566536 @default.
- W2394642790 creator A5018809215 @default.
- W2394642790 creator A5065066504 @default.
- W2394642790 date "2017-02-01" @default.
- W2394642790 modified "2023-10-06" @default.
- W2394642790 title "Tumor-targeting peptides from combinatorial libraries" @default.
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