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- W2395058785 abstract "Trypsin catalyzed hydrolysis of seven new chromogenic arginine substrates, N alpha-benzyloxycarbonyl-L-arginine-3-nitro-5X-anilide (X = H, CF3, SO2CH3, F, Cl, Br and I) were studied. These substrates are suitable for studying electronic effects on trypsin activity. The Km and kcat values for the hydrolysis of each substrate were determined and found to differ significantly for the various substrates. The Hammett plot of the catalytic rate constants gave a straight line with a negative rho value (-0.82) thus indicating that electron withdrawing substituents retard the trypsin catalyzed hydrolysis of the new anilide substrates." @default.
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- W2395058785 date "1987-12-01" @default.
- W2395058785 modified "2023-10-14" @default.
- W2395058785 title "Trypsin catalyzed hydrolysis of new chromogenic arginine substrates." @default.
- W2395058785 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3440026" @default.
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