Matches in SemOpenAlex for { <https://semopenalex.org/work/W2395062988> ?p ?o ?g. }
Showing items 1 to 54 of
54
with 100 items per page.
- W2395062988 endingPage "502" @default.
- W2395062988 startingPage "497" @default.
- W2395062988 abstract "A method based on selected ion monitoring for determination of five monohydroxy metabolites of methaqualone in urine has been worked out. By means of this method the time course of metabolite excretion was studied in three healthy volunteers receiving an oral therapeutic dose of methaqualone. In all subjects the main monohydroxy metabolite was conjugated 4'-hydroxymethaqualone, but the relative importance of the five metabolites showed intersubject variation. Metabolite excretion was still going on, when urine sampling was discontinued after 70 hr. Only small amounts (less than 1% of the dose during 70 hr) of unmetabolized methaqualone were excreted. On the other hand, it was confirmed that methaqualone-N1-oxide is an important metabolite. The presence of a hydroxy methoxy metabolite of methaqualone, very probably 4'-hydroxy-5'-methoxymethaqualone, as a minor metabolite was established by comparison with authentic, synthetic material. 8-Hydroxymethaqualone and 2-nitrobenz-o-toluidide, reported by other groups, could not be detected." @default.
- W2395062988 created "2016-06-24" @default.
- W2395062988 creator A5054053707 @default.
- W2395062988 creator A5058975658 @default.
- W2395062988 date "1977-11-01" @default.
- W2395062988 modified "2023-10-13" @default.
- W2395062988 title "Urinary excretion pattern of methaqualone metabolites in man." @default.
- W2395062988 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21773" @default.
- W2395062988 hasPublicationYear "1977" @default.
- W2395062988 type Work @default.
- W2395062988 sameAs 2395062988 @default.
- W2395062988 citedByCount "6" @default.
- W2395062988 crossrefType "journal-article" @default.
- W2395062988 hasAuthorship W2395062988A5054053707 @default.
- W2395062988 hasAuthorship W2395062988A5058975658 @default.
- W2395062988 hasConcept C10146269 @default.
- W2395062988 hasConcept C185592680 @default.
- W2395062988 hasConcept C2776952961 @default.
- W2395062988 hasConcept C2777477808 @default.
- W2395062988 hasConcept C2780026642 @default.
- W2395062988 hasConcept C43617362 @default.
- W2395062988 hasConcept C55493867 @default.
- W2395062988 hasConcept C71924100 @default.
- W2395062988 hasConcept C98274493 @default.
- W2395062988 hasConceptScore W2395062988C10146269 @default.
- W2395062988 hasConceptScore W2395062988C185592680 @default.
- W2395062988 hasConceptScore W2395062988C2776952961 @default.
- W2395062988 hasConceptScore W2395062988C2777477808 @default.
- W2395062988 hasConceptScore W2395062988C2780026642 @default.
- W2395062988 hasConceptScore W2395062988C43617362 @default.
- W2395062988 hasConceptScore W2395062988C55493867 @default.
- W2395062988 hasConceptScore W2395062988C71924100 @default.
- W2395062988 hasConceptScore W2395062988C98274493 @default.
- W2395062988 hasIssue "6" @default.
- W2395062988 hasLocation W23950629881 @default.
- W2395062988 hasOpenAccess W2395062988 @default.
- W2395062988 hasPrimaryLocation W23950629881 @default.
- W2395062988 hasRelatedWork W1958230997 @default.
- W2395062988 hasRelatedWork W1964936050 @default.
- W2395062988 hasRelatedWork W2017436561 @default.
- W2395062988 hasRelatedWork W2033981589 @default.
- W2395062988 hasRelatedWork W2082818506 @default.
- W2395062988 hasRelatedWork W2158831046 @default.
- W2395062988 hasRelatedWork W2170940607 @default.
- W2395062988 hasRelatedWork W2273147184 @default.
- W2395062988 hasRelatedWork W2395062988 @default.
- W2395062988 hasRelatedWork W2406364491 @default.
- W2395062988 hasVolume "5" @default.
- W2395062988 isParatext "false" @default.
- W2395062988 isRetracted "false" @default.
- W2395062988 magId "2395062988" @default.
- W2395062988 workType "article" @default.