Matches in SemOpenAlex for { <https://semopenalex.org/work/W2395167647> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W2395167647 endingPage "5" @default.
- W2395167647 startingPage "172" @default.
- W2395167647 abstract "Lupus anticoagulant (LA) is an autoantibody that inhibits phospholipid-dependent reactions. Studies on the incidence and prevalence of LA in the pediatric population are lacking. The objective of our study was to determine the incidence and potential risk of complications of LA in children presenting with abnormal partial thromboplastin time (PTT). Our secondary objective was to identify signs, symptoms, and medical history associated with the presence of LA as documented in the literature. We focused on the correlation between signs of LA in the form of laboratory values consistent with bleeding abnormalities and the presence of clinical symptoms of bleeding.We conducted a record-based retrospective analysis of 112 children and adolescents referred to the Department of Hematology/Oncology at Children's Hospital of New Orleans for abnormal coagulation profiles and/or history of mucocutaneous bleeding. Participants were followed up until PTT values normalized.In our study population with suspected bleeding disorder, the preliminary incidence of LA was 21%. We found that resolution of LA correlated with correction of PTT in 90% of patients.To minimize extensive and expensive blood workup, we recommend that screening for LA be included in the evaluation of children with prolonged PTT, even if they have a negative history of bleeding problems." @default.
- W2395167647 created "2016-06-24" @default.
- W2395167647 creator A5015194241 @default.
- W2395167647 creator A5051388864 @default.
- W2395167647 creator A5066133135 @default.
- W2395167647 creator A5066169481 @default.
- W2395167647 date "2016-01-01" @default.
- W2395167647 modified "2023-09-26" @default.
- W2395167647 title "Prevalence and Resolution of Lupus Anticoagulant in Children." @default.
- W2395167647 cites W108868863 @default.
- W2395167647 cites W1534198514 @default.
- W2395167647 cites W1888200383 @default.
- W2395167647 cites W1971166546 @default.
- W2395167647 cites W1990700348 @default.
- W2395167647 cites W2003997429 @default.
- W2395167647 cites W2032162517 @default.
- W2395167647 cites W2054330426 @default.
- W2395167647 cites W2060422033 @default.
- W2395167647 cites W206689509 @default.
- W2395167647 cites W2079220954 @default.
- W2395167647 cites W2120019146 @default.
- W2395167647 cites W2125758043 @default.
- W2395167647 cites W2129075194 @default.
- W2395167647 cites W2134529260 @default.
- W2395167647 cites W2146907889 @default.
- W2395167647 cites W2160597832 @default.
- W2395167647 cites W2214060581 @default.
- W2395167647 cites W2412160625 @default.
- W2395167647 cites W3092642076 @default.
- W2395167647 cites W4230104693 @default.
- W2395167647 cites W73309389 @default.
- W2395167647 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4896663" @default.
- W2395167647 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27303229" @default.
- W2395167647 hasPublicationYear "2016" @default.
- W2395167647 type Work @default.
- W2395167647 sameAs 2395167647 @default.
- W2395167647 citedByCount "1" @default.
- W2395167647 countsByYear W23951676472018 @default.
- W2395167647 crossrefType "journal-article" @default.
- W2395167647 hasAuthorship W2395167647A5015194241 @default.
- W2395167647 hasAuthorship W2395167647A5051388864 @default.
- W2395167647 hasAuthorship W2395167647A5066133135 @default.
- W2395167647 hasAuthorship W2395167647A5066169481 @default.
- W2395167647 hasConcept C120665830 @default.
- W2395167647 hasConcept C121332964 @default.
- W2395167647 hasConcept C126322002 @default.
- W2395167647 hasConcept C156662089 @default.
- W2395167647 hasConcept C167135981 @default.
- W2395167647 hasConcept C187212893 @default.
- W2395167647 hasConcept C194409129 @default.
- W2395167647 hasConcept C2778261982 @default.
- W2395167647 hasConcept C2778382381 @default.
- W2395167647 hasConcept C2779134260 @default.
- W2395167647 hasConcept C2779377019 @default.
- W2395167647 hasConcept C2780022809 @default.
- W2395167647 hasConcept C2780434524 @default.
- W2395167647 hasConcept C2780868729 @default.
- W2395167647 hasConcept C2908647359 @default.
- W2395167647 hasConcept C61511704 @default.
- W2395167647 hasConcept C71924100 @default.
- W2395167647 hasConcept C99454951 @default.
- W2395167647 hasConceptScore W2395167647C120665830 @default.
- W2395167647 hasConceptScore W2395167647C121332964 @default.
- W2395167647 hasConceptScore W2395167647C126322002 @default.
- W2395167647 hasConceptScore W2395167647C156662089 @default.
- W2395167647 hasConceptScore W2395167647C167135981 @default.
- W2395167647 hasConceptScore W2395167647C187212893 @default.
- W2395167647 hasConceptScore W2395167647C194409129 @default.
- W2395167647 hasConceptScore W2395167647C2778261982 @default.
- W2395167647 hasConceptScore W2395167647C2778382381 @default.
- W2395167647 hasConceptScore W2395167647C2779134260 @default.
- W2395167647 hasConceptScore W2395167647C2779377019 @default.
- W2395167647 hasConceptScore W2395167647C2780022809 @default.
- W2395167647 hasConceptScore W2395167647C2780434524 @default.
- W2395167647 hasConceptScore W2395167647C2780868729 @default.
- W2395167647 hasConceptScore W2395167647C2908647359 @default.
- W2395167647 hasConceptScore W2395167647C61511704 @default.
- W2395167647 hasConceptScore W2395167647C71924100 @default.
- W2395167647 hasConceptScore W2395167647C99454951 @default.
- W2395167647 hasIssue "2" @default.
- W2395167647 hasLocation W23951676471 @default.
- W2395167647 hasOpenAccess W2395167647 @default.
- W2395167647 hasPrimaryLocation W23951676471 @default.
- W2395167647 hasRelatedWork W1967491142 @default.
- W2395167647 hasRelatedWork W1995030528 @default.
- W2395167647 hasRelatedWork W2079180127 @default.
- W2395167647 hasRelatedWork W2316604595 @default.
- W2395167647 hasRelatedWork W2395167647 @default.
- W2395167647 hasRelatedWork W2897429415 @default.
- W2395167647 hasRelatedWork W2997507476 @default.
- W2395167647 hasRelatedWork W3203126991 @default.
- W2395167647 hasRelatedWork W395165625 @default.
- W2395167647 hasRelatedWork W4288192279 @default.
- W2395167647 hasVolume "16" @default.
- W2395167647 isParatext "false" @default.
- W2395167647 isRetracted "false" @default.
- W2395167647 magId "2395167647" @default.
- W2395167647 workType "article" @default.