Matches in SemOpenAlex for { <https://semopenalex.org/work/W2395194600> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W2395194600 endingPage "80" @default.
- W2395194600 startingPage "179" @default.
- W2395194600 abstract "In order to investigate whether several DNA lesions (O6-methylguanine, 8-hydroxyguanine, xanthine, an abasic site analogue and hypoxanthine) activate a c-Ha-ras gene and to determine the type of mutations induced by the DNA lesions, they were introduced into a synthetic c-Ha-ras gene by DNA cassette mutagenesis techniques. The modified genes were transfected into mouse NIH3T3 cells and the c-Ha-ras genes present in transformed cells were analysed. O6-methylguanine and xanthine induced a mutation to A, hypoxanthine induced a mutation to G. 8-hydroxyguanine and the abasic site analogue caused random mutations in the modified and adjacent positions. These results indicated that the synthetic c-Ha-ras gene is very useful for the detection of mutations caused by a DNA lesion." @default.
- W2395194600 created "2016-06-24" @default.
- W2395194600 creator A5029219248 @default.
- W2395194600 creator A5032242766 @default.
- W2395194600 creator A5045692779 @default.
- W2395194600 creator A5049584975 @default.
- W2395194600 creator A5064171601 @default.
- W2395194600 creator A5067616418 @default.
- W2395194600 creator A5069937286 @default.
- W2395194600 creator A5072805584 @default.
- W2395194600 creator A5073586456 @default.
- W2395194600 creator A5082449956 @default.
- W2395194600 date "1992-01-01" @default.
- W2395194600 modified "2023-09-23" @default.
- W2395194600 title "Mutations induced by DNA lesions in hot spots of the c-Ha-ras gene." @default.
- W2395194600 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1289809" @default.
- W2395194600 hasPublicationYear "1992" @default.
- W2395194600 type Work @default.
- W2395194600 sameAs 2395194600 @default.
- W2395194600 citedByCount "1" @default.
- W2395194600 crossrefType "journal-article" @default.
- W2395194600 hasAuthorship W2395194600A5029219248 @default.
- W2395194600 hasAuthorship W2395194600A5032242766 @default.
- W2395194600 hasAuthorship W2395194600A5045692779 @default.
- W2395194600 hasAuthorship W2395194600A5049584975 @default.
- W2395194600 hasAuthorship W2395194600A5064171601 @default.
- W2395194600 hasAuthorship W2395194600A5067616418 @default.
- W2395194600 hasAuthorship W2395194600A5069937286 @default.
- W2395194600 hasAuthorship W2395194600A5072805584 @default.
- W2395194600 hasAuthorship W2395194600A5073586456 @default.
- W2395194600 hasAuthorship W2395194600A5082449956 @default.
- W2395194600 hasConcept C104317684 @default.
- W2395194600 hasConcept C134935766 @default.
- W2395194600 hasConcept C150777479 @default.
- W2395194600 hasConcept C153911025 @default.
- W2395194600 hasConcept C16318435 @default.
- W2395194600 hasConcept C181199279 @default.
- W2395194600 hasConcept C185592680 @default.
- W2395194600 hasConcept C2781116151 @default.
- W2395194600 hasConcept C2994225774 @default.
- W2395194600 hasConcept C501734568 @default.
- W2395194600 hasConcept C54009773 @default.
- W2395194600 hasConcept C54355233 @default.
- W2395194600 hasConcept C552990157 @default.
- W2395194600 hasConcept C55493867 @default.
- W2395194600 hasConcept C86803240 @default.
- W2395194600 hasConceptScore W2395194600C104317684 @default.
- W2395194600 hasConceptScore W2395194600C134935766 @default.
- W2395194600 hasConceptScore W2395194600C150777479 @default.
- W2395194600 hasConceptScore W2395194600C153911025 @default.
- W2395194600 hasConceptScore W2395194600C16318435 @default.
- W2395194600 hasConceptScore W2395194600C181199279 @default.
- W2395194600 hasConceptScore W2395194600C185592680 @default.
- W2395194600 hasConceptScore W2395194600C2781116151 @default.
- W2395194600 hasConceptScore W2395194600C2994225774 @default.
- W2395194600 hasConceptScore W2395194600C501734568 @default.
- W2395194600 hasConceptScore W2395194600C54009773 @default.
- W2395194600 hasConceptScore W2395194600C54355233 @default.
- W2395194600 hasConceptScore W2395194600C552990157 @default.
- W2395194600 hasConceptScore W2395194600C55493867 @default.
- W2395194600 hasConceptScore W2395194600C86803240 @default.
- W2395194600 hasIssue "27" @default.
- W2395194600 hasLocation W23951946001 @default.
- W2395194600 hasOpenAccess W2395194600 @default.
- W2395194600 hasPrimaryLocation W23951946001 @default.
- W2395194600 hasRelatedWork W126234363 @default.
- W2395194600 hasRelatedWork W1973004554 @default.
- W2395194600 hasRelatedWork W202910747 @default.
- W2395194600 hasRelatedWork W2083531614 @default.
- W2395194600 hasRelatedWork W2130268149 @default.
- W2395194600 hasRelatedWork W2147428968 @default.
- W2395194600 hasRelatedWork W2350324307 @default.
- W2395194600 hasRelatedWork W2367199598 @default.
- W2395194600 hasRelatedWork W2375289825 @default.
- W2395194600 hasRelatedWork W2395194600 @default.
- W2395194600 isParatext "false" @default.
- W2395194600 isRetracted "false" @default.
- W2395194600 magId "2395194600" @default.
- W2395194600 workType "article" @default.