Matches in SemOpenAlex for { <https://semopenalex.org/work/W2395206557> ?p ?o ?g. }
Showing items 1 to 75 of
75
with 100 items per page.
- W2395206557 endingPage "4" @default.
- W2395206557 startingPage "370" @default.
- W2395206557 abstract "To study the expression and significance of matriptase in different metastatic potential of human ovarian cancer cells.High-metastatic human ovarian cancer cell HO8910PM and ovarian cancer cell HO8910 were collected.The ability of metastatic of the former was stronger than that of the latter. Compared the ability of invasion and migration in HO8910PM and HO8910 by scratch assay and by millicell chamber artificial reconstituted basement membrane invasion assay. Detected the matriptase mRNA and protein expression levels in HO8910PM and HO8910 through reverse transcription(RT)-PCR and immunocytochemistry methods.The 24 hours' migration distance (347 ± 8) µm of HO8910PM cells were significantly higher than that in HO8910 group (154 ± 10) µm (P < 0.01);The number of HO8910PM cells that penetrated the matrigel after 24 hours' incubation were significantly higher than that in HO8910 group (90.7 ± 2.1 vs 63.3 ± 1.5,P < 0.01). The expression of matriptase mRNA in HO8910PM cells was higher than that in HO8910 group (0.72 ± 0.03 vs 0.38 ± 0.04,P < 0.01). The migration was positively correlated with the matriptase mRNA expression levels (r = 0.992, P < 0.01); and the invasiveness was also positively correlated with the matriptase mRNA expression levels (r = 0.973, P < 0.01). As far protein level,the expression of matriptase protein in HO8910PM cells was higher than that in HO8910 group (15.6 ± 0.8 vs 7.6 ± 1.3,P < 0.01). The migration was positively correlated with matriptase protein expression levels (r = 0.971, P < 0.01); And the invasiveness was also positively correlated with the matriptase protein expression levels (r = 0.958, P < 0.01).The relationship between the expression levels of matriptase and the metastatic of ovarian cancer cells may be correlative. The function of matriptase in ovarian cancer cells metastatic mechanism still need to be confirmed." @default.
- W2395206557 created "2016-06-24" @default.
- W2395206557 creator A5026655998 @default.
- W2395206557 creator A5034480243 @default.
- W2395206557 creator A5035222810 @default.
- W2395206557 creator A5052432001 @default.
- W2395206557 creator A5056394671 @default.
- W2395206557 creator A5058593146 @default.
- W2395206557 date "2013-05-01" @default.
- W2395206557 modified "2023-09-23" @default.
- W2395206557 title "[Expression and significance of matriptase in ovarian cancer cells with diverse metastatic potential]." @default.
- W2395206557 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24016481" @default.
- W2395206557 hasPublicationYear "2013" @default.
- W2395206557 type Work @default.
- W2395206557 sameAs 2395206557 @default.
- W2395206557 citedByCount "1" @default.
- W2395206557 countsByYear W23952065572016 @default.
- W2395206557 crossrefType "journal-article" @default.
- W2395206557 hasAuthorship W2395206557A5026655998 @default.
- W2395206557 hasAuthorship W2395206557A5034480243 @default.
- W2395206557 hasAuthorship W2395206557A5035222810 @default.
- W2395206557 hasAuthorship W2395206557A5052432001 @default.
- W2395206557 hasAuthorship W2395206557A5056394671 @default.
- W2395206557 hasAuthorship W2395206557A5058593146 @default.
- W2395206557 hasConcept C104317684 @default.
- W2395206557 hasConcept C105580179 @default.
- W2395206557 hasConcept C121608353 @default.
- W2395206557 hasConcept C126322002 @default.
- W2395206557 hasConcept C1491633281 @default.
- W2395206557 hasConcept C153911025 @default.
- W2395206557 hasConcept C16685009 @default.
- W2395206557 hasConcept C185592680 @default.
- W2395206557 hasConcept C2778608917 @default.
- W2395206557 hasConcept C2779013556 @default.
- W2395206557 hasConcept C2780427987 @default.
- W2395206557 hasConcept C502942594 @default.
- W2395206557 hasConcept C55493867 @default.
- W2395206557 hasConcept C71924100 @default.
- W2395206557 hasConcept C86803240 @default.
- W2395206557 hasConceptScore W2395206557C104317684 @default.
- W2395206557 hasConceptScore W2395206557C105580179 @default.
- W2395206557 hasConceptScore W2395206557C121608353 @default.
- W2395206557 hasConceptScore W2395206557C126322002 @default.
- W2395206557 hasConceptScore W2395206557C1491633281 @default.
- W2395206557 hasConceptScore W2395206557C153911025 @default.
- W2395206557 hasConceptScore W2395206557C16685009 @default.
- W2395206557 hasConceptScore W2395206557C185592680 @default.
- W2395206557 hasConceptScore W2395206557C2778608917 @default.
- W2395206557 hasConceptScore W2395206557C2779013556 @default.
- W2395206557 hasConceptScore W2395206557C2780427987 @default.
- W2395206557 hasConceptScore W2395206557C502942594 @default.
- W2395206557 hasConceptScore W2395206557C55493867 @default.
- W2395206557 hasConceptScore W2395206557C71924100 @default.
- W2395206557 hasConceptScore W2395206557C86803240 @default.
- W2395206557 hasIssue "5" @default.
- W2395206557 hasLocation W23952065571 @default.
- W2395206557 hasOpenAccess W2395206557 @default.
- W2395206557 hasPrimaryLocation W23952065571 @default.
- W2395206557 hasRelatedWork W2168388492 @default.
- W2395206557 hasRelatedWork W2333142390 @default.
- W2395206557 hasRelatedWork W2581349936 @default.
- W2395206557 hasRelatedWork W2623306262 @default.
- W2395206557 hasRelatedWork W2801461341 @default.
- W2395206557 hasRelatedWork W2922713651 @default.
- W2395206557 hasRelatedWork W2992277018 @default.
- W2395206557 hasRelatedWork W3114532332 @default.
- W2395206557 hasRelatedWork W4285048863 @default.
- W2395206557 hasRelatedWork W4286560383 @default.
- W2395206557 hasVolume "48" @default.
- W2395206557 isParatext "false" @default.
- W2395206557 isRetracted "false" @default.
- W2395206557 magId "2395206557" @default.
- W2395206557 workType "article" @default.