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- W239527653 abstract "Avascular necrosis (AVN), also termed as osteonecrosis or aseptic necrosis, is a process caused by direct and indirect damage to the vascular supply of the involved bone.1-5 Clinical course of the disease is usually progressive and causes significant pain and limitation of movement. Trauma causes AVN by the obvious direct interruption of the vascular supply, but there are a variety of underlying systemic disorders associated with the development of AVN via indirect vascular compromise. The known risk factors include corticosteroid use, alcohol abuse, smoking, sickle cell anemia, coagulopathies, systemic lupus erythematosus, hypercholesterolemia, Gaucher ' s disease, chronic pancreatitis, and hyper-triglyceridemia.3 It is very difficult to define reasons of AVN in individual patient, because most of the patients had multiple risk factors for AVN. On the other hand, approximately 10%-20% of AVN cases have no known risk factors and are classified as idiopathic AVN." @default.
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- W239527653 date "2004-09-01" @default.
- W239527653 modified "2023-09-26" @default.
- W239527653 title "Human immunodeficiency virus and avascular necrosis of the femoral head: a case report." @default.
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