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- W2395293354 abstract "In a paper published last year (Yudkin, 1945) I suggested that patients with malaria who do not respond well to oral mepacrine therapy might show a low urinary excretion of the drug. In such cases parenteral administration might be of value. Since then I have examined specimens of urine from hundreds of individuals on suppressive or therapeutic mepacrine and had not found one in whomn there was a failure of absorption, nor has it been reported by other workers. In August, 1945, however, such a case was seen in a West African military hospital. The patient was a young European naval rating with malaria who did not respond to large doses of mepacrine orally; he excreted only extremely small quantities of the drug in the Lirine and responded rapidly to a few small doses intramuLscularly." @default.
- W2395293354 created "2016-06-24" @default.
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- W2395293354 date "1946-02-23" @default.
- W2395293354 modified "2023-09-23" @default.
- W2395293354 title "Non-absorption of mepacrine: description of a case." @default.
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- W2395293354 hasPublicationYear "1946" @default.
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