Matches in SemOpenAlex for { <https://semopenalex.org/work/W2395331619> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W2395331619 endingPage "231" @default.
- W2395331619 startingPage "227" @default.
- W2395331619 abstract "Monospecific anti-[rat alpha-foetoprotein(alpha-FP)] immunoglobulin G was coupled to CNBr-activated Sepharose-4B (4.5 mg/ml packed volume of gel) to yield an adsorbent. The immunoaffinity column was used to isolate alpha-FP from neonatal-rat skin. Purified skin alpha-FP was found to be immunologically and electrophoretically similar to serum alpha-FP. It yielded a single band with mol.wt. 68000 on sodium dodecyl sulphate/polyacrylamide-gel electrophoresis. However, on polyacrylamide-gel electrophoresis under non-denaturing conditions, the alpha-FP displayed slow- and fast-moving variants similar to those observed in serum alpha-FP. A Scatchard plot of oestradiol binding to the alpha-FP yielded an association constant of 2.5 X 10(9)M-1 by dextran-coated-charcoal and 0.75 X 10(8)M-1 by Sephadex-gel-filtration procedures respectively. Skin explants from newborn rats were found to incorporate [14C]leucine into immunoprecipitable intracellular alpha-FP. Cycloheximide inhibited the synthesis of alpha-FP in skin explant culture. Our results indicate that newborn-rat skin contains alpha-FP that is similar to serum alpha-FP and which may arise in neonatal-rat skin as a result of synthesis in situ." @default.
- W2395331619 created "2016-06-24" @default.
- W2395331619 creator A5023009454 @default.
- W2395331619 creator A5044246350 @default.
- W2395331619 creator A5058150220 @default.
- W2395331619 date "1983-10-15" @default.
- W2395331619 modified "2023-10-16" @default.
- W2395331619 title "Isolation, characterization and synthesis of α-foetoprotein from neonatal-rat skin" @default.
- W2395331619 cites W1586317568 @default.
- W2395331619 cites W1625660792 @default.
- W2395331619 cites W1775749144 @default.
- W2395331619 cites W1965439667 @default.
- W2395331619 cites W1975149236 @default.
- W2395331619 cites W1978848425 @default.
- W2395331619 cites W1980876896 @default.
- W2395331619 cites W1983123525 @default.
- W2395331619 cites W1986779104 @default.
- W2395331619 cites W1990986783 @default.
- W2395331619 cites W1992205230 @default.
- W2395331619 cites W1995135269 @default.
- W2395331619 cites W1999609998 @default.
- W2395331619 cites W2015785578 @default.
- W2395331619 cites W2017475728 @default.
- W2395331619 cites W2019244584 @default.
- W2395331619 cites W2040130095 @default.
- W2395331619 cites W2043587716 @default.
- W2395331619 cites W2090691291 @default.
- W2395331619 cites W2091906071 @default.
- W2395331619 cites W44724797 @default.
- W2395331619 doi "https://doi.org/10.1042/bj2160227" @default.
- W2395331619 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1152490" @default.
- W2395331619 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6197062" @default.
- W2395331619 hasPublicationYear "1983" @default.
- W2395331619 type Work @default.
- W2395331619 sameAs 2395331619 @default.
- W2395331619 citedByCount "0" @default.
- W2395331619 crossrefType "journal-article" @default.
- W2395331619 hasAuthorship W2395331619A5023009454 @default.
- W2395331619 hasAuthorship W2395331619A5044246350 @default.
- W2395331619 hasAuthorship W2395331619A5058150220 @default.
- W2395331619 hasBestOaLocation W23953316192 @default.
- W2395331619 hasConcept C101660505 @default.
- W2395331619 hasConcept C116084860 @default.
- W2395331619 hasConcept C153911025 @default.
- W2395331619 hasConcept C159110408 @default.
- W2395331619 hasConcept C163994747 @default.
- W2395331619 hasConcept C181199279 @default.
- W2395331619 hasConcept C185592680 @default.
- W2395331619 hasConcept C193363816 @default.
- W2395331619 hasConcept C2775944032 @default.
- W2395331619 hasConcept C2778128677 @default.
- W2395331619 hasConcept C3675279 @default.
- W2395331619 hasConcept C43617362 @default.
- W2395331619 hasConcept C49453240 @default.
- W2395331619 hasConcept C55493867 @default.
- W2395331619 hasConcept C64943373 @default.
- W2395331619 hasConcept C71924100 @default.
- W2395331619 hasConcept C86803240 @default.
- W2395331619 hasConceptScore W2395331619C101660505 @default.
- W2395331619 hasConceptScore W2395331619C116084860 @default.
- W2395331619 hasConceptScore W2395331619C153911025 @default.
- W2395331619 hasConceptScore W2395331619C159110408 @default.
- W2395331619 hasConceptScore W2395331619C163994747 @default.
- W2395331619 hasConceptScore W2395331619C181199279 @default.
- W2395331619 hasConceptScore W2395331619C185592680 @default.
- W2395331619 hasConceptScore W2395331619C193363816 @default.
- W2395331619 hasConceptScore W2395331619C2775944032 @default.
- W2395331619 hasConceptScore W2395331619C2778128677 @default.
- W2395331619 hasConceptScore W2395331619C3675279 @default.
- W2395331619 hasConceptScore W2395331619C43617362 @default.
- W2395331619 hasConceptScore W2395331619C49453240 @default.
- W2395331619 hasConceptScore W2395331619C55493867 @default.
- W2395331619 hasConceptScore W2395331619C64943373 @default.
- W2395331619 hasConceptScore W2395331619C71924100 @default.
- W2395331619 hasConceptScore W2395331619C86803240 @default.
- W2395331619 hasIssue "1" @default.
- W2395331619 hasLocation W23953316191 @default.
- W2395331619 hasLocation W23953316192 @default.
- W2395331619 hasLocation W23953316193 @default.
- W2395331619 hasLocation W23953316194 @default.
- W2395331619 hasOpenAccess W2395331619 @default.
- W2395331619 hasPrimaryLocation W23953316191 @default.
- W2395331619 hasRelatedWork W1495447187 @default.
- W2395331619 hasRelatedWork W1943335296 @default.
- W2395331619 hasRelatedWork W1954232397 @default.
- W2395331619 hasRelatedWork W2001321907 @default.
- W2395331619 hasRelatedWork W2022994535 @default.
- W2395331619 hasRelatedWork W2054862544 @default.
- W2395331619 hasRelatedWork W2072220682 @default.
- W2395331619 hasRelatedWork W2427479962 @default.
- W2395331619 hasRelatedWork W3021106527 @default.
- W2395331619 hasRelatedWork W4362726510 @default.
- W2395331619 hasVolume "216" @default.
- W2395331619 isParatext "false" @default.
- W2395331619 isRetracted "false" @default.
- W2395331619 magId "2395331619" @default.
- W2395331619 workType "article" @default.