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- W2395351333 abstract "When the extracellular Na+ was replaced by lithium (Li+) the frequency of the impulses elicited by stretching the stretch receptor of crayfish was changed and then inhibited. This effect was not due to the lack of extracellular Na+. Higher firing rate facilitated and low extracellular K+ delayed the Li+ effect. Ouabain alone (10-4 M) changed the impulse activity in a similar manner to Li+ replacement. Ouabain (10-5 M) decreased the rate of recovery during wash-out after Li+ replacement. The Li+-induced increase in the frequency of the impulse activity was probably the result of a lower intracellular K+ concentration, the block of the spike activity being due to the accumulation of Li+ in the cell. The Na+ pump participated in the recovery of the spike activity after Li+ replacement." @default.
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- W2395351333 date "1970-12-01" @default.
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- W2395351333 title "Studies on the Mechanism of Action of Lithium Ions" @default.
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- W2395351333 doi "https://doi.org/10.1111/j.1748-1716.1970.tb04819.x" @default.
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