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- W2395622046 abstract "ABSTRACT: The major input and output pathways of the mammalian striatum have been well established. Recent studies have identified a number of neurotransmitters used by these pathways as well as by striatal interneurons, and have begun to unravel their synaptic connections. The major output neurons have been identified as medium spiny neurons which contain ɣ-aminobutyric acid (GABA), endogeneous opioids, and substance P. These neurons project to the pallidum and substantia nigra in a topographic and probably chemically organized manner. The major striatal afferents from the cerebral cortex, thalamus, and substantia nigra terminate, at least in part, on these striatal projection neurons. Striatal interneurons contain acetylcholine, GABA, and somatostatin plus neuropeptide Y, and appear to synapse on striatal projection neurons. In recent years, much activity has been directed to the neurochemical and hodological heterogeneities which occur at a macroscopic level in the striatum. This has led to the concept of a patch-matrix organization in the striatum." @default.
- W2395622046 created "2016-06-24" @default.
- W2395622046 creator A5034663097 @default.
- W2395622046 creator A5040825701 @default.
- W2395622046 creator A5042605439 @default.
- W2395622046 date "1987-08-01" @default.
- W2395622046 modified "2023-09-27" @default.
- W2395622046 title "Neurotransmitters in the Mammalian Striatum: Neuronal Circuits and Heterogeneity" @default.
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