Matches in SemOpenAlex for { <https://semopenalex.org/work/W23956445> ?p ?o ?g. }
- W23956445 endingPage "41" @default.
- W23956445 startingPage "33" @default.
- W23956445 abstract "In Xenopus, growth factors of the TGF-beta, FGF and Wnt oncogene families have been proposed to play a role in generating embryonic pattern. In this paper we examine potential interactions between the bFGF and Xwnt-8 signaling pathways in the induction and dorsal-ventral patterning of mesoderm. Injection of Xwnt-8 mRNA into 2-cell Xenopus embryos does not induce mesoderm formation in animal cap ectoderm isolated from these embryos at the blastula stage, but alters the response of this tissue to mesoderm induction by bFGF. While animal cap explants isolated from non-injected embryos differentiate to form ventral types of mesoderm and muscle in response to bFGF, explants from Xwnt-8 injected embryos form dorsal mesodermal and neural tissues in response to the same concentration of bFGF, even if the ectoderm is isolated from the prospective ventral sides of embryos or from UV-ventralized animals. Our results support a model whereby dorso-ventral mesodermal patterning can be attained by a single mesoderm inducing agent, possibly bFGF, which is uniformly distributed across the prospective dorsal-ventral axis, and which acts in concert with a dorsally localized signal, possibly a Wnt protein, which either alters the response of ectoderm to induction or modifies the character of mesoderm after its induction." @default.
- W23956445 created "2016-06-24" @default.
- W23956445 creator A5024528673 @default.
- W23956445 creator A5075832689 @default.
- W23956445 creator A5082917536 @default.
- W23956445 date "1992-01-01" @default.
- W23956445 modified "2023-09-25" @default.
- W23956445 title "Xwnt-8 modifies the character of mesoderm induced by bFGF in isolated Xenopus ectoderm." @default.
- W23956445 cites W1772194966 @default.
- W23956445 cites W1859128757 @default.
- W23956445 cites W1860007525 @default.
- W23956445 cites W1874287342 @default.
- W23956445 cites W1879408402 @default.
- W23956445 cites W1904018663 @default.
- W23956445 cites W1920825899 @default.
- W23956445 cites W1927305112 @default.
- W23956445 cites W194137483 @default.
- W23956445 cites W1945116336 @default.
- W23956445 cites W1964629878 @default.
- W23956445 cites W1965918354 @default.
- W23956445 cites W1967080927 @default.
- W23956445 cites W1970341768 @default.
- W23956445 cites W1975301960 @default.
- W23956445 cites W1978411854 @default.
- W23956445 cites W1980315452 @default.
- W23956445 cites W1981213410 @default.
- W23956445 cites W1982031676 @default.
- W23956445 cites W1986925729 @default.
- W23956445 cites W1989721036 @default.
- W23956445 cites W2013548303 @default.
- W23956445 cites W2023772121 @default.
- W23956445 cites W2027569400 @default.
- W23956445 cites W2039610005 @default.
- W23956445 cites W2048835534 @default.
- W23956445 cites W2055830220 @default.
- W23956445 cites W2057798589 @default.
- W23956445 cites W2091637225 @default.
- W23956445 cites W2094741224 @default.
- W23956445 cites W2104000274 @default.
- W23956445 cites W2125423296 @default.
- W23956445 cites W2132048446 @default.
- W23956445 cites W2151834696 @default.
- W23956445 cites W2165200226 @default.
- W23956445 cites W2183471011 @default.
- W23956445 cites W2265750209 @default.
- W23956445 cites W2404996591 @default.
- W23956445 cites W2442642743 @default.
- W23956445 doi "https://doi.org/10.1002/j.1460-2075.1992.tb05024.x" @default.
- W23956445 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/556422" @default.
- W23956445 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1740111" @default.
- W23956445 hasPublicationYear "1992" @default.
- W23956445 type Work @default.
- W23956445 sameAs 23956445 @default.
- W23956445 citedByCount "151" @default.
- W23956445 countsByYear W239564452013 @default.
- W23956445 countsByYear W239564452015 @default.
- W23956445 countsByYear W239564452016 @default.
- W23956445 countsByYear W239564452018 @default.
- W23956445 countsByYear W239564452020 @default.
- W23956445 countsByYear W239564452022 @default.
- W23956445 crossrefType "journal-article" @default.
- W23956445 hasAuthorship W23956445A5024528673 @default.
- W23956445 hasAuthorship W23956445A5075832689 @default.
- W23956445 hasAuthorship W23956445A5082917536 @default.
- W23956445 hasBestOaLocation W239564452 @default.
- W23956445 hasConcept C104317684 @default.
- W23956445 hasConcept C105702510 @default.
- W23956445 hasConcept C122428330 @default.
- W23956445 hasConcept C126322002 @default.
- W23956445 hasConcept C129536746 @default.
- W23956445 hasConcept C134018914 @default.
- W23956445 hasConcept C137620995 @default.
- W23956445 hasConcept C145103041 @default.
- W23956445 hasConcept C196843134 @default.
- W23956445 hasConcept C2779329299 @default.
- W23956445 hasConcept C2779535977 @default.
- W23956445 hasConcept C2780915607 @default.
- W23956445 hasConcept C54355233 @default.
- W23956445 hasConcept C6047887 @default.
- W23956445 hasConcept C62478195 @default.
- W23956445 hasConcept C66332042 @default.
- W23956445 hasConcept C71924100 @default.
- W23956445 hasConcept C83330619 @default.
- W23956445 hasConcept C86803240 @default.
- W23956445 hasConcept C87073359 @default.
- W23956445 hasConcept C95444343 @default.
- W23956445 hasConceptScore W23956445C104317684 @default.
- W23956445 hasConceptScore W23956445C105702510 @default.
- W23956445 hasConceptScore W23956445C122428330 @default.
- W23956445 hasConceptScore W23956445C126322002 @default.
- W23956445 hasConceptScore W23956445C129536746 @default.
- W23956445 hasConceptScore W23956445C134018914 @default.
- W23956445 hasConceptScore W23956445C137620995 @default.
- W23956445 hasConceptScore W23956445C145103041 @default.
- W23956445 hasConceptScore W23956445C196843134 @default.
- W23956445 hasConceptScore W23956445C2779329299 @default.
- W23956445 hasConceptScore W23956445C2779535977 @default.
- W23956445 hasConceptScore W23956445C2780915607 @default.