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• W2395806832 abstract "GABAA receptors are the major inhibitory neurotransmitter receptors in the brain. They are heteropentamers that are typically classified according to their α subunits. By rendering each of the benzodiazepine-sensitive α subunits (α1, α2, α3, and α5) insensitive to modulation by classical benzodiazepines by His to Arg point mutations in knock-in mice, we were able to identify behavioral functions mediated by different GABAA receptor subtypes, which led to the development of novel therapeutic strategies. In this chapter, we provide a largely chronological overview on behavioral studies on GABAA receptor mutant mice at the Institute of Pharmacology and Toxicology at the University of Zurich." @default.
• W2395806832 created "2016-06-24" @default.
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• W2395806832 date "2015-01-01" @default.
• W2395806832 modified "2023-09-30" @default.
• W2395806832 title "Behavioral Functions of GABAA Receptor Subtypes - The Zurich Experience" @default.
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• W2395806832 doi "https://doi.org/10.1016/bs.apha.2014.10.001" @default.
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