Matches in SemOpenAlex for { <https://semopenalex.org/work/W2395873902> ?p ?o ?g. }
Showing items 1 to 64 of
64
with 100 items per page.
- W2395873902 endingPage "279" @default.
- W2395873902 startingPage "269" @default.
- W2395873902 abstract "Soluble antigen was prepared from adult worms and microfilariae of Onchocerca volvulus. In 27 patients clinically characterized as having generalized type (17) and localized reaction type (10) onchocerciasis, the response to this antigen was assessed in vivo by skin testing and in vitro by leucocyte migration inhibition assay. Three varieties of skin hypersensitivity were observed: Immediate, Arthus-type and delayed or type IV hypersensitivity. The first 2 occurred in all patients, but type IV hypersensitivity was noted only in 10, eight of whom had localized reactive type onchocerciasis, whilst the other 2 had mild generalized lesions which had for the most part healed with treatment. The leucocyte migration inhibition assay showed a spectrum of responsiveness with significant inhibition in the presence of antigen in 8 patients with localized lesions and in 2 others with mild generalized disease which had largely healed.--The specificity of the skin reaction and leucocyte migration inhibition to the antigen used was confirmed by the results obtained when a control group of 18 subjects, with no evidence of previous filarial infection, was similarly tested. 16 of them showed no skin hypersensitivity and 2 had a doubtful immediate reaction. No significant inhibition of leucocyte migration in the presence of antigen was noted in this group." @default.
- W2395873902 created "2016-06-24" @default.
- W2395873902 creator A5046104340 @default.
- W2395873902 date "1978-09-01" @default.
- W2395873902 modified "2023-09-22" @default.
- W2395873902 title "Immunological studies on onchocerciasis. Varying skin hypersensitivity and leucocyte migration inhibition in a clinical spectrum of the disease." @default.
- W2395873902 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31781" @default.
- W2395873902 hasPublicationYear "1978" @default.
- W2395873902 type Work @default.
- W2395873902 sameAs 2395873902 @default.
- W2395873902 citedByCount "13" @default.
- W2395873902 crossrefType "journal-article" @default.
- W2395873902 hasAuthorship W2395873902A5046104340 @default.
- W2395873902 hasConcept C147483822 @default.
- W2395873902 hasConcept C150903083 @default.
- W2395873902 hasConcept C203014093 @default.
- W2395873902 hasConcept C207001950 @default.
- W2395873902 hasConcept C2779027325 @default.
- W2395873902 hasConcept C2780727990 @default.
- W2395873902 hasConcept C2993280485 @default.
- W2395873902 hasConcept C3017924640 @default.
- W2395873902 hasConcept C71924100 @default.
- W2395873902 hasConcept C86803240 @default.
- W2395873902 hasConceptScore W2395873902C147483822 @default.
- W2395873902 hasConceptScore W2395873902C150903083 @default.
- W2395873902 hasConceptScore W2395873902C203014093 @default.
- W2395873902 hasConceptScore W2395873902C207001950 @default.
- W2395873902 hasConceptScore W2395873902C2779027325 @default.
- W2395873902 hasConceptScore W2395873902C2780727990 @default.
- W2395873902 hasConceptScore W2395873902C2993280485 @default.
- W2395873902 hasConceptScore W2395873902C3017924640 @default.
- W2395873902 hasConceptScore W2395873902C71924100 @default.
- W2395873902 hasConceptScore W2395873902C86803240 @default.
- W2395873902 hasIssue "3" @default.
- W2395873902 hasLocation W23958739021 @default.
- W2395873902 hasOpenAccess W2395873902 @default.
- W2395873902 hasPrimaryLocation W23958739021 @default.
- W2395873902 hasRelatedWork W1528098311 @default.
- W2395873902 hasRelatedWork W1579035193 @default.
- W2395873902 hasRelatedWork W1810110600 @default.
- W2395873902 hasRelatedWork W192337254 @default.
- W2395873902 hasRelatedWork W1977188587 @default.
- W2395873902 hasRelatedWork W1991994149 @default.
- W2395873902 hasRelatedWork W1997590146 @default.
- W2395873902 hasRelatedWork W2067453119 @default.
- W2395873902 hasRelatedWork W2072116732 @default.
- W2395873902 hasRelatedWork W2083805299 @default.
- W2395873902 hasRelatedWork W2100837269 @default.
- W2395873902 hasRelatedWork W2105758850 @default.
- W2395873902 hasRelatedWork W2155622605 @default.
- W2395873902 hasRelatedWork W2169591310 @default.
- W2395873902 hasRelatedWork W2217545727 @default.
- W2395873902 hasRelatedWork W2227690332 @default.
- W2395873902 hasRelatedWork W2400849558 @default.
- W2395873902 hasRelatedWork W2427974379 @default.
- W2395873902 hasRelatedWork W2469333153 @default.
- W2395873902 hasRelatedWork W79314742 @default.
- W2395873902 hasVolume "35" @default.
- W2395873902 isParatext "false" @default.
- W2395873902 isRetracted "false" @default.
- W2395873902 magId "2395873902" @default.
- W2395873902 workType "article" @default.