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- W2395963388 abstract "Acute erythroleukemia is an aggressive leukemia derived from a multipotential stem cell. Three subtypes have been described: M6a with >3 30% blasts of the nonerythrocytic component, M6b with >30% pronormoblasts of the erythrocytic elements, and M6c with >30% blasts and >30% pronormoblasts by the aforementioned exclusion criteria. The poor prognosis associated with this disorder positively correlates with a high pronormoblast:mye- loblast ratio, “unfavorable” cytogenetic aberrations, a high proliferative index, and the presence of P-glycoprotein expression (multi-drug resistance phenotype). Chemotherapeutic regimens, directed toward these specific parameters, should be devised in order to improve the characteristically poor outcome of this patient population." @default.
- W2395963388 created "2016-06-24" @default.
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- W2395963388 date "2000-03-01" @default.
- W2395963388 modified "2023-09-27" @default.
- W2395963388 title "The Acute Erythroleukemias" @default.
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- W2395963388 doi "https://doi.org/10.1016/s0272-2712(18)30080-5" @default.
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