Matches in SemOpenAlex for { <https://semopenalex.org/work/W2396171160> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W2396171160 endingPage "6" @default.
- W2396171160 startingPage "282" @default.
- W2396171160 abstract "Four novel analogues of (E)-5-(2-bromovinyl)-2'-deoxyuridine [(E)-BrVUdR]--the (E)- and (Z)-isomer of 5-(2-fluorovinyl)-UdR (FVUdR), (Z)-5-(2-carboxy-2-fluorovinyl)-UdR [(Z)-COOH-FVUdR], and (E)-5-(2-ethoxyvinyl)-UdR [(E)-EOVUdR] were compared with the reference compounds (E)-BrVUdR and 5-vinyl-UdR (VUdR) for their inhibitory effects on plaque formation of herpes simplex virus type 1 (HSV-1 strain 77) and type 2 (HSV-2 strain 82) in human embryonic lung fibroblast (HELF) cell cultures. (Z)-FVUdR and (Z)-COOH-FVUdR were completely inactive against HSV-1 and HSV-2 (ID50 greater than 500 microM). For the other analogues the following order of decreasing potency was found: (E)-BrVUdR greater than VUdR greater than (E)-FVUdR much greater than (E)-EOVUdR (against HSV-1) and VUdR much greater than (E)-BrVUdR greater than (E)-FVUdR much greater than (E)-EOVUdR (against HSV-2)." @default.
- W2396171160 created "2016-06-24" @default.
- W2396171160 creator A5000339855 @default.
- W2396171160 creator A5022229932 @default.
- W2396171160 creator A5074023473 @default.
- W2396171160 date "1984-07-01" @default.
- W2396171160 modified "2023-09-23" @default.
- W2396171160 title "Differential antiherpes activity of the (E)-and (Z)-isomers of 5-(2-fluorovinyl)-2'-deoxyuridine (FVUdR)." @default.
- W2396171160 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6148852" @default.
- W2396171160 hasPublicationYear "1984" @default.
- W2396171160 type Work @default.
- W2396171160 sameAs 2396171160 @default.
- W2396171160 citedByCount "5" @default.
- W2396171160 countsByYear W23961711602020 @default.
- W2396171160 crossrefType "journal-article" @default.
- W2396171160 hasAuthorship W2396171160A5000339855 @default.
- W2396171160 hasAuthorship W2396171160A5022229932 @default.
- W2396171160 hasAuthorship W2396171160A5074023473 @default.
- W2396171160 hasConcept C105702510 @default.
- W2396171160 hasConcept C153911025 @default.
- W2396171160 hasConcept C159047783 @default.
- W2396171160 hasConcept C185592680 @default.
- W2396171160 hasConcept C202751555 @default.
- W2396171160 hasConcept C2522874641 @default.
- W2396171160 hasConcept C2777111502 @default.
- W2396171160 hasConcept C2778022156 @default.
- W2396171160 hasConcept C2780381497 @default.
- W2396171160 hasConcept C2781196997 @default.
- W2396171160 hasConcept C54355233 @default.
- W2396171160 hasConcept C552990157 @default.
- W2396171160 hasConcept C55493867 @default.
- W2396171160 hasConcept C57992300 @default.
- W2396171160 hasConcept C71240020 @default.
- W2396171160 hasConcept C81885089 @default.
- W2396171160 hasConcept C86803240 @default.
- W2396171160 hasConceptScore W2396171160C105702510 @default.
- W2396171160 hasConceptScore W2396171160C153911025 @default.
- W2396171160 hasConceptScore W2396171160C159047783 @default.
- W2396171160 hasConceptScore W2396171160C185592680 @default.
- W2396171160 hasConceptScore W2396171160C202751555 @default.
- W2396171160 hasConceptScore W2396171160C2522874641 @default.
- W2396171160 hasConceptScore W2396171160C2777111502 @default.
- W2396171160 hasConceptScore W2396171160C2778022156 @default.
- W2396171160 hasConceptScore W2396171160C2780381497 @default.
- W2396171160 hasConceptScore W2396171160C2781196997 @default.
- W2396171160 hasConceptScore W2396171160C54355233 @default.
- W2396171160 hasConceptScore W2396171160C552990157 @default.
- W2396171160 hasConceptScore W2396171160C55493867 @default.
- W2396171160 hasConceptScore W2396171160C57992300 @default.
- W2396171160 hasConceptScore W2396171160C71240020 @default.
- W2396171160 hasConceptScore W2396171160C81885089 @default.
- W2396171160 hasConceptScore W2396171160C86803240 @default.
- W2396171160 hasIssue "4" @default.
- W2396171160 hasLocation W23961711601 @default.
- W2396171160 hasOpenAccess W2396171160 @default.
- W2396171160 hasPrimaryLocation W23961711601 @default.
- W2396171160 hasRelatedWork W1702322095 @default.
- W2396171160 hasRelatedWork W1979810128 @default.
- W2396171160 hasRelatedWork W1980513567 @default.
- W2396171160 hasRelatedWork W1981045519 @default.
- W2396171160 hasRelatedWork W1998940927 @default.
- W2396171160 hasRelatedWork W2005523247 @default.
- W2396171160 hasRelatedWork W2044753800 @default.
- W2396171160 hasRelatedWork W2396171160 @default.
- W2396171160 hasRelatedWork W2429868034 @default.
- W2396171160 hasRelatedWork W3138602129 @default.
- W2396171160 hasVolume "28" @default.
- W2396171160 isParatext "false" @default.
- W2396171160 isRetracted "false" @default.
- W2396171160 magId "2396171160" @default.
- W2396171160 workType "article" @default.