Matches in SemOpenAlex for { <https://semopenalex.org/work/W2396564320> ?p ?o ?g. }
Showing items 1 to 74 of
74
with 100 items per page.
- W2396564320 endingPage "7" @default.
- W2396564320 startingPage "373" @default.
- W2396564320 abstract "To characterize the effect of the amacrine cell-selective toxin N-methyl-D-aspartate (NMDA) on ocular growth in chicks.Single injections of NMDA in doses ranging from 20 to 2000 nmol in 20 microL of sterile saline were made into the vitreous chamber of one eye of 7-day-old white leghorn chicks (six chicks per group); the contralateral (control) eye was injected with saline. Six NMDA-treated eyes were also deprived of form vision by applying a translucent goggle 7 days after treatment, to determine whether myopia could still be induced or enhanced in NMDA-treated eyes.Axial length, equatorial diameter and refractive error, measured immediately after and 7, 14, 21, 28 and 35 days after treatment.NMDA-treated eyes became myopic within 7 days of treatment and remained so until at least 35 days after treatment. During this time the eyes continued to grow but could not be induced to become more myopic by depriving them of patterned images. The half-maximal effective dose of NMDA was calculated to be 670 nmol, 7 days after treatment.NMDA-induced excitotoxicity destroys retinal pathways by which patterned visual stimuli restrain ocular growth in the chick." @default.
- W2396564320 created "2016-06-24" @default.
- W2396564320 creator A5007111786 @default.
- W2396564320 creator A5047793216 @default.
- W2396564320 creator A5063139808 @default.
- W2396564320 date "1997-10-01" @default.
- W2396564320 modified "2023-09-23" @default.
- W2396564320 title "N-methyl-D-aspartate-induced excitotoxicity causes myopia in hatched chicks." @default.
- W2396564320 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9363340" @default.
- W2396564320 hasPublicationYear "1997" @default.
- W2396564320 type Work @default.
- W2396564320 sameAs 2396564320 @default.
- W2396564320 citedByCount "13" @default.
- W2396564320 countsByYear W23965643202012 @default.
- W2396564320 countsByYear W23965643202015 @default.
- W2396564320 countsByYear W23965643202016 @default.
- W2396564320 countsByYear W23965643202017 @default.
- W2396564320 countsByYear W23965643202018 @default.
- W2396564320 countsByYear W23965643202021 @default.
- W2396564320 crossrefType "journal-article" @default.
- W2396564320 hasAuthorship W2396564320A5007111786 @default.
- W2396564320 hasAuthorship W2396564320A5047793216 @default.
- W2396564320 hasAuthorship W2396564320A5063139808 @default.
- W2396564320 hasConcept C105702510 @default.
- W2396564320 hasConcept C118487528 @default.
- W2396564320 hasConcept C126322002 @default.
- W2396564320 hasConcept C169760540 @default.
- W2396564320 hasConcept C170493617 @default.
- W2396564320 hasConcept C2776148792 @default.
- W2396564320 hasConcept C2777093970 @default.
- W2396564320 hasConcept C2777397205 @default.
- W2396564320 hasConcept C2780827179 @default.
- W2396564320 hasConcept C2781012912 @default.
- W2396564320 hasConcept C2781135284 @default.
- W2396564320 hasConcept C42219234 @default.
- W2396564320 hasConcept C67018056 @default.
- W2396564320 hasConcept C71924100 @default.
- W2396564320 hasConcept C86803240 @default.
- W2396564320 hasConceptScore W2396564320C105702510 @default.
- W2396564320 hasConceptScore W2396564320C118487528 @default.
- W2396564320 hasConceptScore W2396564320C126322002 @default.
- W2396564320 hasConceptScore W2396564320C169760540 @default.
- W2396564320 hasConceptScore W2396564320C170493617 @default.
- W2396564320 hasConceptScore W2396564320C2776148792 @default.
- W2396564320 hasConceptScore W2396564320C2777093970 @default.
- W2396564320 hasConceptScore W2396564320C2777397205 @default.
- W2396564320 hasConceptScore W2396564320C2780827179 @default.
- W2396564320 hasConceptScore W2396564320C2781012912 @default.
- W2396564320 hasConceptScore W2396564320C2781135284 @default.
- W2396564320 hasConceptScore W2396564320C42219234 @default.
- W2396564320 hasConceptScore W2396564320C67018056 @default.
- W2396564320 hasConceptScore W2396564320C71924100 @default.
- W2396564320 hasConceptScore W2396564320C86803240 @default.
- W2396564320 hasIssue "6" @default.
- W2396564320 hasLocation W23965643201 @default.
- W2396564320 hasOpenAccess W2396564320 @default.
- W2396564320 hasPrimaryLocation W23965643201 @default.
- W2396564320 hasRelatedWork W1979657680 @default.
- W2396564320 hasRelatedWork W2026592202 @default.
- W2396564320 hasRelatedWork W2040386224 @default.
- W2396564320 hasRelatedWork W2051796263 @default.
- W2396564320 hasRelatedWork W2057311179 @default.
- W2396564320 hasRelatedWork W2076176473 @default.
- W2396564320 hasRelatedWork W2354182071 @default.
- W2396564320 hasRelatedWork W2403214295 @default.
- W2396564320 hasRelatedWork W3167687272 @default.
- W2396564320 hasRelatedWork W4212826853 @default.
- W2396564320 hasVolume "32" @default.
- W2396564320 isParatext "false" @default.
- W2396564320 isRetracted "false" @default.
- W2396564320 magId "2396564320" @default.
- W2396564320 workType "article" @default.