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- W2396640821 endingPage "4180" @default.
- W2396640821 startingPage "4167" @default.
- W2396640821 abstract "Metalloproteins contain actives sites with intricate structures that perform specific functions with high selectivity and efficiency. The complexity of these systems complicates the study of their function and the understanding of the properties that give rise to their reactivity. One approach that has contributed to the current level of understanding of their biological function is the study of synthetic constructs that mimic one or more aspects of the native metalloproteins. These systems allow individual contributions to the structure and function to be analyzed and also permit spectroscopic characterization of the metal cofactors without complications from the protein environment. This Current Topic is a review of synthetic constructs as probes for understanding the biological activation of small molecules. These topics are developed from the perspective of seminal molecular design breakthroughs from the past that provide the foundation for the systems used today." @default.
- W2396640821 created "2016-06-24" @default.
- W2396640821 creator A5021086016 @default.
- W2396640821 creator A5028690228 @default.
- W2396640821 creator A5051656727 @default.
- W2396640821 date "2015-06-30" @default.
- W2396640821 modified "2023-09-29" @default.
- W2396640821 title "Lessons from Nature: A Bio-Inspired Approach to Molecular Design" @default.
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