Matches in SemOpenAlex for { <https://semopenalex.org/work/W2396693881> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W2396693881 endingPage "699" @default.
- W2396693881 startingPage "691" @default.
- W2396693881 abstract "The concentration of diacylglycerols in rat liver was measured by a newly developed procedure that entailed a) freeze-clamping of the liver in situ, b) lipid extraction with dimyristoylglycerol as an internal standard, c) thin-layer chromatography, and d) gas-liquid chromatography. Molecular species of diacylglycerol and total diacylglycerols were quantified. The average level of diacylglycerol in livers of chow-fed rats was 102 micrograms/g wet wt, equivalent to about 180 nmol/g wet wt. A high-carbohydrate fat-free diet, known to increase the rate of fatty acid synthesis, greatly increased the liver diacylglycerol concentration relative to the level observed in rats fed laboratory chow. Diacylglycerol molecular species that contained 16-carbon fatty acids were most markedly elevated. Liver triacylglycerol, free cholesterol, and esterified cholesterol were concurrently increased. Molecular species of triacylglycerols and cholesteryl esters that contained 16-carbon fatty acids were elevated to the greatest degree. The concentrations of total triacylglycerol and cholesteryl esters exhibited a high correlation in the livers of all animals studied, suggesting their coexistence in metabolic pools, predominantly the cores of lipid droplets and newly assembled very low density lipoprotein particles. The correlation of liver diacylglycerol and triacylglycerol contents in the chow-fed rats suggests that the diacylglycerol concentration may be a rate-determining factor in triacylglycerol synthesis when diacylglycerol levels are in the observed range of 70-150 micrograms/g wet wt. In conclusion, when the rates of fatty acid synthesis and hence triacylglycerol synthesis are increased in the liver, the steady state concentrations of diacylglycerols are also elevated.(ABSTRACT TRUNCATED AT 400 WORDS)" @default.
- W2396693881 created "2016-06-24" @default.
- W2396693881 creator A5082472967 @default.
- W2396693881 creator A5084817043 @default.
- W2396693881 date "1989-05-01" @default.
- W2396693881 modified "2023-09-25" @default.
- W2396693881 title "Elevation of liver diacylglycerols and molecular species of diacylglycerols in rats fed a lipogenic diet." @default.
- W2396693881 cites W1493283928 @default.
- W2396693881 cites W1585120633 @default.
- W2396693881 cites W1590462946 @default.
- W2396693881 cites W1609520994 @default.
- W2396693881 cites W164548000 @default.
- W2396693881 cites W1676701054 @default.
- W2396693881 cites W174750072 @default.
- W2396693881 cites W1985118950 @default.
- W2396693881 cites W2001692359 @default.
- W2396693881 cites W2027704731 @default.
- W2396693881 cites W2034241238 @default.
- W2396693881 cites W2043458856 @default.
- W2396693881 cites W2053360220 @default.
- W2396693881 cites W2056272446 @default.
- W2396693881 cites W2065220901 @default.
- W2396693881 cites W2078489711 @default.
- W2396693881 cites W2138418832 @default.
- W2396693881 cites W2149154963 @default.
- W2396693881 cites W2173345687 @default.
- W2396693881 cites W2185828038 @default.
- W2396693881 cites W2185845830 @default.
- W2396693881 cites W2186410182 @default.
- W2396693881 cites W2211449861 @default.
- W2396693881 cites W2278310395 @default.
- W2396693881 cites W2301037150 @default.
- W2396693881 cites W2329380505 @default.
- W2396693881 cites W2343083312 @default.
- W2396693881 cites W2415450113 @default.
- W2396693881 cites W4231733340 @default.
- W2396693881 doi "https://doi.org/10.1016/s0022-2275(20)38329-2" @default.
- W2396693881 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2760543" @default.
- W2396693881 hasPublicationYear "1989" @default.
- W2396693881 type Work @default.
- W2396693881 sameAs 2396693881 @default.
- W2396693881 citedByCount "9" @default.
- W2396693881 countsByYear W23966938812014 @default.
- W2396693881 crossrefType "journal-article" @default.
- W2396693881 hasAuthorship W2396693881A5082472967 @default.
- W2396693881 hasAuthorship W2396693881A5084817043 @default.
- W2396693881 hasBestOaLocation W23966938811 @default.
- W2396693881 hasConcept C126322002 @default.
- W2396693881 hasConcept C134018914 @default.
- W2396693881 hasConcept C141359234 @default.
- W2396693881 hasConcept C185592680 @default.
- W2396693881 hasConcept C4733338 @default.
- W2396693881 hasConcept C55493867 @default.
- W2396693881 hasConcept C71924100 @default.
- W2396693881 hasConcept C86803240 @default.
- W2396693881 hasConceptScore W2396693881C126322002 @default.
- W2396693881 hasConceptScore W2396693881C134018914 @default.
- W2396693881 hasConceptScore W2396693881C141359234 @default.
- W2396693881 hasConceptScore W2396693881C185592680 @default.
- W2396693881 hasConceptScore W2396693881C4733338 @default.
- W2396693881 hasConceptScore W2396693881C55493867 @default.
- W2396693881 hasConceptScore W2396693881C71924100 @default.
- W2396693881 hasConceptScore W2396693881C86803240 @default.
- W2396693881 hasIssue "5" @default.
- W2396693881 hasLocation W23966938811 @default.
- W2396693881 hasLocation W23966938812 @default.
- W2396693881 hasOpenAccess W2396693881 @default.
- W2396693881 hasPrimaryLocation W23966938811 @default.
- W2396693881 hasRelatedWork W1592691368 @default.
- W2396693881 hasRelatedWork W1823058265 @default.
- W2396693881 hasRelatedWork W1972831620 @default.
- W2396693881 hasRelatedWork W1992393423 @default.
- W2396693881 hasRelatedWork W2015867011 @default.
- W2396693881 hasRelatedWork W2055300824 @default.
- W2396693881 hasRelatedWork W2078141101 @default.
- W2396693881 hasRelatedWork W2104696040 @default.
- W2396693881 hasRelatedWork W2130981205 @default.
- W2396693881 hasRelatedWork W2144650717 @default.
- W2396693881 hasVolume "30" @default.
- W2396693881 isParatext "false" @default.
- W2396693881 isRetracted "false" @default.
- W2396693881 magId "2396693881" @default.
- W2396693881 workType "article" @default.