Matches in SemOpenAlex for { <https://semopenalex.org/work/W2397029031> ?p ?o ?g. }
- W2397029031 endingPage "171" @default.
- W2397029031 startingPage "163" @default.
- W2397029031 abstract "The performances of three neutral static coatings (hydroxypropyl cellulose, polyethylene oxide and poly(N,N-dimethylacrylamide) have been evaluated in order to determine the binding constants of the complexes formed between four polycationic compounds (piperazine derivatives) and four cyclodextrins of pharmaceutical interest (β-CD, HP-β-CD, Me-β-CD and sulfobutyl ether-β-CD) by affinity capillary electrophoresis. The physically-adsorbed poly(N,N-dimethylacrylamide) coating proves to be the more efficient to mask the silanol groups of the capillary wall since the lowest electroosmotic flow was measured for this coating. Moreover, it drastically reduces the adsorption of the compounds since it allows a correct repeatability of their migration time, higher efficiencies of the peaks and no baseline shift. Then, it was verified for four complexes that this coating allows a correct determination of the binding constants avoiding the CD adsorption which is responsible of an undervaluation of binding constants. The highest binding constants are obtained using the anionic sulfobutyl ether-β-CD (SBE-β-CD). The structure of the complex formed between the tacrine derivative and the SBE-β-CD was further investigated through 2D ROESY NMR experiments and structure-binding constant relationships. Results suggest that the inclusion in the SBE-β-CD cavity occurs through the aliphatic ring portion of the tacrine moiety." @default.
- W2397029031 created "2016-06-24" @default.
- W2397029031 creator A5048948927 @default.
- W2397029031 creator A5063781523 @default.
- W2397029031 creator A5068389054 @default.
- W2397029031 creator A5074599262 @default.
- W2397029031 creator A5075828635 @default.
- W2397029031 creator A5082987387 @default.
- W2397029031 date "2016-07-01" @default.
- W2397029031 modified "2023-10-17" @default.
- W2397029031 title "Evaluation of three neutral capillary coatings for the determination of analyte-cyclodextrin binding constants by affinity capillary electrophoresis. Application to N , N ⿲-disubstituted piperazine derivatives." @default.
- W2397029031 cites W1966132354 @default.
- W2397029031 cites W1970049372 @default.
- W2397029031 cites W1970878676 @default.
- W2397029031 cites W1971691078 @default.
- W2397029031 cites W1971841136 @default.
- W2397029031 cites W1972746006 @default.
- W2397029031 cites W1977131953 @default.
- W2397029031 cites W1981111847 @default.
- W2397029031 cites W1988441913 @default.
- W2397029031 cites W1990543384 @default.
- W2397029031 cites W1992510922 @default.
- W2397029031 cites W1999373065 @default.
- W2397029031 cites W2002374932 @default.
- W2397029031 cites W2012960885 @default.
- W2397029031 cites W2019701067 @default.
- W2397029031 cites W2033102119 @default.
- W2397029031 cites W2034020376 @default.
- W2397029031 cites W2036138053 @default.
- W2397029031 cites W2036812147 @default.
- W2397029031 cites W2045324409 @default.
- W2397029031 cites W2049655875 @default.
- W2397029031 cites W2055091943 @default.
- W2397029031 cites W2055443367 @default.
- W2397029031 cites W2059134849 @default.
- W2397029031 cites W2063314780 @default.
- W2397029031 cites W2077006735 @default.
- W2397029031 cites W2078436408 @default.
- W2397029031 cites W2083811444 @default.
- W2397029031 cites W2092843759 @default.
- W2397029031 cites W2092865989 @default.
- W2397029031 cites W2114499390 @default.
- W2397029031 cites W2152865924 @default.
- W2397029031 cites W2152895185 @default.
- W2397029031 cites W2157110881 @default.
- W2397029031 cites W2162942392 @default.
- W2397029031 cites W2318354588 @default.
- W2397029031 cites W2321972685 @default.
- W2397029031 cites W4211053799 @default.
- W2397029031 cites W4239647016 @default.
- W2397029031 cites W4247852925 @default.
- W2397029031 doi "https://doi.org/10.1016/j.chroma.2016.05.090" @default.
- W2397029031 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27286645" @default.
- W2397029031 hasPublicationYear "2016" @default.
- W2397029031 type Work @default.
- W2397029031 sameAs 2397029031 @default.
- W2397029031 citedByCount "8" @default.
- W2397029031 countsByYear W23970290312016 @default.
- W2397029031 countsByYear W23970290312017 @default.
- W2397029031 countsByYear W23970290312018 @default.
- W2397029031 countsByYear W23970290312019 @default.
- W2397029031 countsByYear W23970290312020 @default.
- W2397029031 countsByYear W23970290312022 @default.
- W2397029031 countsByYear W23970290312023 @default.
- W2397029031 crossrefType "journal-article" @default.
- W2397029031 hasAuthorship W2397029031A5048948927 @default.
- W2397029031 hasAuthorship W2397029031A5063781523 @default.
- W2397029031 hasAuthorship W2397029031A5068389054 @default.
- W2397029031 hasAuthorship W2397029031A5074599262 @default.
- W2397029031 hasAuthorship W2397029031A5075828635 @default.
- W2397029031 hasAuthorship W2397029031A5082987387 @default.
- W2397029031 hasBestOaLocation W23970290312 @default.
- W2397029031 hasConcept C107824862 @default.
- W2397029031 hasConcept C150394285 @default.
- W2397029031 hasConcept C168191866 @default.
- W2397029031 hasConcept C178790620 @default.
- W2397029031 hasConcept C184651966 @default.
- W2397029031 hasConcept C185592680 @default.
- W2397029031 hasConcept C188027245 @default.
- W2397029031 hasConcept C2775863688 @default.
- W2397029031 hasConcept C2776201271 @default.
- W2397029031 hasConcept C2776568683 @default.
- W2397029031 hasConcept C2779251873 @default.
- W2397029031 hasConcept C2779433975 @default.
- W2397029031 hasConcept C2780407432 @default.
- W2397029031 hasConcept C2900643 @default.
- W2397029031 hasConcept C32786932 @default.
- W2397029031 hasConcept C43617362 @default.
- W2397029031 hasConcept C55493867 @default.
- W2397029031 hasConceptScore W2397029031C107824862 @default.
- W2397029031 hasConceptScore W2397029031C150394285 @default.
- W2397029031 hasConceptScore W2397029031C168191866 @default.
- W2397029031 hasConceptScore W2397029031C178790620 @default.
- W2397029031 hasConceptScore W2397029031C184651966 @default.
- W2397029031 hasConceptScore W2397029031C185592680 @default.
- W2397029031 hasConceptScore W2397029031C188027245 @default.
- W2397029031 hasConceptScore W2397029031C2775863688 @default.
- W2397029031 hasConceptScore W2397029031C2776201271 @default.