Matches in SemOpenAlex for { <https://semopenalex.org/work/W2397044265> ?p ?o ?g. }
Showing items 1 to 62 of
62
with 100 items per page.
- W2397044265 endingPage "7" @default.
- W2397044265 startingPage "481" @default.
- W2397044265 abstract "The pharmacodynamic and nephrotoxic effects of cefamandole were investigated. Cefamandole at concentrations of 512 and 1024 micrograms/ml bath caused complete relaxation in isolated guinea pig ileum and rabbit duodenum, respectively. Concentrations of 2048 and 4096 micrograms cefamandole/ml bath caused marked stimulation in force and frequency of rat uterine muscle in all stages of sex cycle. Cefamandole in all tested concentrations did not induce any response on isolated guinea pig tracheal chain or isolated rabbit aortic strip. Cefamandole in concentrations of 256 to 1024 micrograms/ml bath as well as 256 and 512 micrograms/ml cannula produced marked inhibition on isolated guinea pig auricles and rabbit heart, respectively. The effect of graded increased concentrations on isolated frog gastrocnemius muscle, frog rectus abdominis muscle and rat phrenic nerve hemidiaphragm was recorded. Cefamandole in a dose of 53.2 mg/kg b. wt. in anaesthetized dogs caused very marked hypotensive effects and decrease in rate of respiration. Single intramuscular injection of cefamandole in a therapeutic (23.3 mg/kg b. wt.) and double therapeutic (46.6 mg/kg.b. wt.) doses in rabbits had no effect on electrocardiographic parameters among a period of 8 hours after injection. Effects of cefamandole on serum and urine concentrations of creatinine, urea, sodium, potassium, calcium, glucose and protein as well as clearance tests were investigated in rats." @default.
- W2397044265 created "2016-06-24" @default.
- W2397044265 creator A5005038618 @default.
- W2397044265 creator A5006187458 @default.
- W2397044265 creator A5039439330 @default.
- W2397044265 creator A5067705912 @default.
- W2397044265 creator A5075114695 @default.
- W2397044265 date "1997-11-01" @default.
- W2397044265 modified "2023-09-27" @default.
- W2397044265 title "Some pharmacodynamic and biochemical aspects of cefamandole." @default.
- W2397044265 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9429324" @default.
- W2397044265 hasPublicationYear "1997" @default.
- W2397044265 type Work @default.
- W2397044265 sameAs 2397044265 @default.
- W2397044265 citedByCount "6" @default.
- W2397044265 countsByYear W23970442652012 @default.
- W2397044265 countsByYear W23970442652013 @default.
- W2397044265 countsByYear W23970442652014 @default.
- W2397044265 countsByYear W23970442652015 @default.
- W2397044265 crossrefType "journal-article" @default.
- W2397044265 hasAuthorship W2397044265A5005038618 @default.
- W2397044265 hasAuthorship W2397044265A5006187458 @default.
- W2397044265 hasAuthorship W2397044265A5039439330 @default.
- W2397044265 hasAuthorship W2397044265A5067705912 @default.
- W2397044265 hasAuthorship W2397044265A5075114695 @default.
- W2397044265 hasConcept C126322002 @default.
- W2397044265 hasConcept C134018914 @default.
- W2397044265 hasConcept C185592680 @default.
- W2397044265 hasConcept C2780463255 @default.
- W2397044265 hasConcept C501593827 @default.
- W2397044265 hasConcept C55493867 @default.
- W2397044265 hasConcept C64778159 @default.
- W2397044265 hasConcept C71924100 @default.
- W2397044265 hasConceptScore W2397044265C126322002 @default.
- W2397044265 hasConceptScore W2397044265C134018914 @default.
- W2397044265 hasConceptScore W2397044265C185592680 @default.
- W2397044265 hasConceptScore W2397044265C2780463255 @default.
- W2397044265 hasConceptScore W2397044265C501593827 @default.
- W2397044265 hasConceptScore W2397044265C55493867 @default.
- W2397044265 hasConceptScore W2397044265C64778159 @default.
- W2397044265 hasConceptScore W2397044265C71924100 @default.
- W2397044265 hasIssue "11" @default.
- W2397044265 hasLocation W23970442651 @default.
- W2397044265 hasOpenAccess W2397044265 @default.
- W2397044265 hasPrimaryLocation W23970442651 @default.
- W2397044265 hasRelatedWork W1966504330 @default.
- W2397044265 hasRelatedWork W1966775726 @default.
- W2397044265 hasRelatedWork W1979139803 @default.
- W2397044265 hasRelatedWork W2030889776 @default.
- W2397044265 hasRelatedWork W2037631372 @default.
- W2397044265 hasRelatedWork W2063957970 @default.
- W2397044265 hasRelatedWork W2064362993 @default.
- W2397044265 hasRelatedWork W2090960426 @default.
- W2397044265 hasRelatedWork W2132898409 @default.
- W2397044265 hasRelatedWork W2391409986 @default.
- W2397044265 hasVolume "104" @default.
- W2397044265 isParatext "false" @default.
- W2397044265 isRetracted "false" @default.
- W2397044265 magId "2397044265" @default.
- W2397044265 workType "article" @default.