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- W2397071043 abstract "OBJECTIVE: To explore the association between monoamine oxidase A (MAOA) variable number tandem repeat (VNTR) polymorphism and major depression in Chinese Han population. METHODS: Polymerase chain reaction was used to genotype MAOA VNTR polymorphism. A total of 512 major depression patients and 566 normal controls were recruited in our study. These patients were also assessed using the 14-item Hamilton anxiety scale. RESULTS The allele frequency of MAOA VNTR was not significantly different between the male/female major depression patients and the normal controls. Compared with the normal controls, MAOA VNTR genotype was significantly more frequent in female major depression patients (P=0.002), but not in male patients (P=0.17). MAOA VNTR-L carrier was also associated with fear symptom in female patients (P=0.0056). CONCLUSION: MAOA gene is associated with the major depression in Chinese Han population, especially among female patients." @default.
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- W2397071043 date "2009-12-01" @default.
- W2397071043 modified "2023-09-23" @default.
- W2397071043 title "Association between monoamine oxidase A gene and major depression in Chinese Han population" @default.
- W2397071043 doi "https://doi.org/10.3881/j.issn.1000-503x.2009.06.015" @default.
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