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- W2397124227 abstract "Effect of TCCM on prednisone acetate induced osteoporotic rat was evaluated by single photon absorptiometry.24 male Sprague-Dawley (SD) rats at 3 months of age and weighing 345～347g were used in this study and randomly divided into control,hormone-TCCM groups.The hormonal group was fed prednisone acetate (4.5mg/kg,ig)twice a week and the hormone-TCCM group given TCCM(5g/kg,ig)6days per week besides prednisone acetate.After 90 days,single photon absorptiometric measurement were made on femurs of three groups of rats.Results showed that bone mineral density(BMI) in proximal,middle and distant segments of hormonal rats was respectively decreased by 12.4%(P<0.05),13.9%(P<0.05) and 11.9%(P<0.05)ub comparison with control,and the BMD in proximal,middle and distant segments of hormone-TCCM rats was separately increased by 25.9%(P<0.01),34.4%(P<0.01)and 30.6%(P<0.01)when compared with hormonal rats. These data suggested that TCCM could prevent prednisone acetate-induced osteoporosis in rats." @default.
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- W2397124227 date "1996-12-01" @default.
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- W2397124227 title "Studies on the effect of total coumarin of common cnidium (Cnidium monnieri)(TCCM)on prednisone acetate-induced osteoporotic rat by single photon absorptiometry" @default.
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