Matches in SemOpenAlex for { <https://semopenalex.org/work/W2397177111> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W2397177111 startingPage "139" @default.
- W2397177111 abstract "UNLABELLED The aim of the work was evaluation of efficacy of fenspiride b.i.d. on the number of exacerbations and the time to the first exacerbation in patients with chronic bronchitis. MATERIAL AND METHODS Randomized, multicentre study controlled versus placebo was carried out in 12 centers in Poland. All patients, 89 females and 68 males aged between 20 and 74, were treated with fenspiride at the dose of 160 mg/day for a period of 6 months. The following symptoms were recorded every month in order to evaluate the therapeutic efficacy: sputum quality and quantity, cough intensity, dyspnea and bronchospasm. Based on these symptoms diagnosis of exacerbation was performed according to American Thoracic Society criteria. RESULTS Quality and quantity of sputum and cough significantly improved in the fenspiride group (comparing to the placebo group p= 0.027 and p = 0.049 adequately for sputum and cough). A significant difference between groups was observed in the number of exacerbation episodes and their duration. In the fenspiride group there were 0.53 episodes of exacerbation compared with 1.12 episodes in the placebo group (p = 0.038). Mean duration of exacerbation was 3.3 days in the fenspiride group and 7.3 days in the placebo treated patients (p = 0.034). Time to the first exacerbation differed between groups, but this difference was not statistically significant. Number of side effects observed did not differ between groups. CONCLUSION Fenspiride treatment was assessed as relatively effective in terms of influence on exacerbations, and well tolerated during six month therapy." @default.
- W2397177111 created "2016-06-24" @default.
- W2397177111 creator A5005670648 @default.
- W2397177111 creator A5020422942 @default.
- W2397177111 creator A5021443626 @default.
- W2397177111 creator A5030258312 @default.
- W2397177111 creator A5045336869 @default.
- W2397177111 creator A5048989920 @default.
- W2397177111 creator A5068012713 @default.
- W2397177111 creator A5079413142 @default.
- W2397177111 creator A5088930514 @default.
- W2397177111 date "2005-08-01" @default.
- W2397177111 modified "2023-09-26" @default.
- W2397177111 title "The effect of fenspiride on the number of exacerbations and the time of first exacerbation in patients with chronic bronchitis" @default.
- W2397177111 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16245418" @default.
- W2397177111 hasPublicationYear "2005" @default.
- W2397177111 type Work @default.
- W2397177111 sameAs 2397177111 @default.
- W2397177111 citedByCount "0" @default.
- W2397177111 crossrefType "journal-article" @default.
- W2397177111 hasAuthorship W2397177111A5005670648 @default.
- W2397177111 hasAuthorship W2397177111A5020422942 @default.
- W2397177111 hasAuthorship W2397177111A5021443626 @default.
- W2397177111 hasAuthorship W2397177111A5030258312 @default.
- W2397177111 hasAuthorship W2397177111A5045336869 @default.
- W2397177111 hasAuthorship W2397177111A5048989920 @default.
- W2397177111 hasAuthorship W2397177111A5068012713 @default.
- W2397177111 hasAuthorship W2397177111A5079413142 @default.
- W2397177111 hasAuthorship W2397177111A5088930514 @default.
- W2397177111 hasConcept C126322002 @default.
- W2397177111 hasConcept C142724271 @default.
- W2397177111 hasConcept C168563851 @default.
- W2397177111 hasConcept C204787440 @default.
- W2397177111 hasConcept C27081682 @default.
- W2397177111 hasConcept C2776301714 @default.
- W2397177111 hasConcept C2777014857 @default.
- W2397177111 hasConcept C2781069245 @default.
- W2397177111 hasConcept C2992694001 @default.
- W2397177111 hasConcept C42219234 @default.
- W2397177111 hasConcept C71924100 @default.
- W2397177111 hasConceptScore W2397177111C126322002 @default.
- W2397177111 hasConceptScore W2397177111C142724271 @default.
- W2397177111 hasConceptScore W2397177111C168563851 @default.
- W2397177111 hasConceptScore W2397177111C204787440 @default.
- W2397177111 hasConceptScore W2397177111C27081682 @default.
- W2397177111 hasConceptScore W2397177111C2776301714 @default.
- W2397177111 hasConceptScore W2397177111C2777014857 @default.
- W2397177111 hasConceptScore W2397177111C2781069245 @default.
- W2397177111 hasConceptScore W2397177111C2992694001 @default.
- W2397177111 hasConceptScore W2397177111C42219234 @default.
- W2397177111 hasConceptScore W2397177111C71924100 @default.
- W2397177111 hasIssue "110" @default.
- W2397177111 hasLocation W23971771111 @default.
- W2397177111 hasLocation W23971771112 @default.
- W2397177111 hasOpenAccess W2397177111 @default.
- W2397177111 hasPrimaryLocation W23971771111 @default.
- W2397177111 hasRelatedWork W120910910 @default.
- W2397177111 hasRelatedWork W1858551023 @default.
- W2397177111 hasRelatedWork W1989625574 @default.
- W2397177111 hasRelatedWork W2028274288 @default.
- W2397177111 hasRelatedWork W2074961489 @default.
- W2397177111 hasRelatedWork W2116200516 @default.
- W2397177111 hasRelatedWork W2359213891 @default.
- W2397177111 hasRelatedWork W2366229848 @default.
- W2397177111 hasRelatedWork W2396736266 @default.
- W2397177111 hasRelatedWork W2416363015 @default.
- W2397177111 hasRelatedWork W2418620840 @default.
- W2397177111 hasRelatedWork W2475024111 @default.
- W2397177111 hasRelatedWork W2562287737 @default.
- W2397177111 hasRelatedWork W2900957524 @default.
- W2397177111 hasRelatedWork W2990307311 @default.
- W2397177111 hasRelatedWork W2992858290 @default.
- W2397177111 hasRelatedWork W3029426531 @default.
- W2397177111 hasRelatedWork W3045743315 @default.
- W2397177111 hasRelatedWork W1952574676 @default.
- W2397177111 hasRelatedWork W2341540424 @default.
- W2397177111 hasVolume "19" @default.
- W2397177111 isParatext "false" @default.
- W2397177111 isRetracted "false" @default.
- W2397177111 magId "2397177111" @default.
- W2397177111 workType "article" @default.