Matches in SemOpenAlex for { <https://semopenalex.org/work/W2397315759> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W2397315759 abstract "Curcumin, obtained from turmeric, has several biological properties to make it a desirable template for drug development. A lipophilic derivative of curcumin, diacetyl curcumin (DAC) and a hydrophilic derivative, diglutaryl curcumin (DGC) were synthesized and their in vivo analgesic and anti-inflammatory activities were compared with those of curcumin and aspirin. The in vitro anti-cancer activities of curcumin and the two derivatives against three cell cancer lines were compared with those against a non-cancerous cell line. The inhibitory effects were comparable to each other and nearing that of curcumin while they showed low inhibitory effect towards the non-cancerous cell line. The mouse tail flick assay showed that curcumin, DAC and DGC increased latency time. DGC was most effective as an analgesic, even more so than aspirin. The maximum percentage effect (MPE) was highest with DGC at 3 hours. The carrageenan induced paw edema model indicated anti-inflammatory activity of all three curcumin formulations. The percentage inhibition of paw edema was maximum for DAC, followed by aspirin and curcumin." @default.
- W2397315759 created "2016-06-24" @default.
- W2397315759 creator A5000000300 @default.
- W2397315759 creator A5002933821 @default.
- W2397315759 creator A5083417399 @default.
- W2397315759 creator A5088506485 @default.
- W2397315759 date "2013-03-01" @default.
- W2397315759 modified "2023-09-30" @default.
- W2397315759 title "Evaluation of the in vivo Anti-inflammatory and Analgesic and in vitro Anti-cancer Activities of Curcumin and its Derivatives" @default.
- W2397315759 cites W1967578143 @default.
- W2397315759 cites W1981819970 @default.
- W2397315759 cites W2026012172 @default.
- W2397315759 cites W2037222034 @default.
- W2397315759 cites W2068821865 @default.
- W2397315759 cites W2070878775 @default.
- W2397315759 cites W2088496138 @default.
- W2397315759 cites W2116660246 @default.
- W2397315759 cites W2409746082 @default.
- W2397315759 doi "https://doi.org/10.1177/1934578x1300800321" @default.
- W2397315759 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23678811" @default.
- W2397315759 hasPublicationYear "2013" @default.
- W2397315759 type Work @default.
- W2397315759 sameAs 2397315759 @default.
- W2397315759 citedByCount "16" @default.
- W2397315759 countsByYear W23973157592013 @default.
- W2397315759 countsByYear W23973157592015 @default.
- W2397315759 countsByYear W23973157592017 @default.
- W2397315759 countsByYear W23973157592018 @default.
- W2397315759 countsByYear W23973157592019 @default.
- W2397315759 countsByYear W23973157592020 @default.
- W2397315759 countsByYear W23973157592021 @default.
- W2397315759 countsByYear W23973157592022 @default.
- W2397315759 countsByYear W23973157592023 @default.
- W2397315759 crossrefType "journal-article" @default.
- W2397315759 hasAuthorship W2397315759A5000000300 @default.
- W2397315759 hasAuthorship W2397315759A5002933821 @default.
- W2397315759 hasAuthorship W2397315759A5083417399 @default.
- W2397315759 hasAuthorship W2397315759A5088506485 @default.
- W2397315759 hasBestOaLocation W23973157591 @default.
- W2397315759 hasConcept C150903083 @default.
- W2397315759 hasConcept C185592680 @default.
- W2397315759 hasConcept C202751555 @default.
- W2397315759 hasConcept C207001950 @default.
- W2397315759 hasConcept C2777628954 @default.
- W2397315759 hasConcept C2778250585 @default.
- W2397315759 hasConcept C2779703632 @default.
- W2397315759 hasConcept C2780820201 @default.
- W2397315759 hasConcept C2781227287 @default.
- W2397315759 hasConcept C55493867 @default.
- W2397315759 hasConcept C71924100 @default.
- W2397315759 hasConcept C86803240 @default.
- W2397315759 hasConcept C98274493 @default.
- W2397315759 hasConceptScore W2397315759C150903083 @default.
- W2397315759 hasConceptScore W2397315759C185592680 @default.
- W2397315759 hasConceptScore W2397315759C202751555 @default.
- W2397315759 hasConceptScore W2397315759C207001950 @default.
- W2397315759 hasConceptScore W2397315759C2777628954 @default.
- W2397315759 hasConceptScore W2397315759C2778250585 @default.
- W2397315759 hasConceptScore W2397315759C2779703632 @default.
- W2397315759 hasConceptScore W2397315759C2780820201 @default.
- W2397315759 hasConceptScore W2397315759C2781227287 @default.
- W2397315759 hasConceptScore W2397315759C55493867 @default.
- W2397315759 hasConceptScore W2397315759C71924100 @default.
- W2397315759 hasConceptScore W2397315759C86803240 @default.
- W2397315759 hasConceptScore W2397315759C98274493 @default.
- W2397315759 hasLocation W23973157591 @default.
- W2397315759 hasLocation W23973157592 @default.
- W2397315759 hasOpenAccess W2397315759 @default.
- W2397315759 hasPrimaryLocation W23973157591 @default.
- W2397315759 hasRelatedWork W2010993586 @default.
- W2397315759 hasRelatedWork W2075380566 @default.
- W2397315759 hasRelatedWork W2082288510 @default.
- W2397315759 hasRelatedWork W2102912467 @default.
- W2397315759 hasRelatedWork W2149761207 @default.
- W2397315759 hasRelatedWork W2239698145 @default.
- W2397315759 hasRelatedWork W2273613011 @default.
- W2397315759 hasRelatedWork W2419071470 @default.
- W2397315759 hasRelatedWork W2504070227 @default.
- W2397315759 hasRelatedWork W2604974488 @default.
- W2397315759 hasRelatedWork W2740587383 @default.
- W2397315759 hasRelatedWork W2763628669 @default.
- W2397315759 hasRelatedWork W2773183513 @default.
- W2397315759 hasRelatedWork W2891545232 @default.
- W2397315759 hasRelatedWork W2897654008 @default.
- W2397315759 hasRelatedWork W3081720212 @default.
- W2397315759 hasRelatedWork W3118329847 @default.
- W2397315759 hasRelatedWork W3131156105 @default.
- W2397315759 hasRelatedWork W324379331 @default.
- W2397315759 hasRelatedWork W2288727246 @default.
- W2397315759 isParatext "false" @default.
- W2397315759 isRetracted "false" @default.
- W2397315759 magId "2397315759" @default.
- W2397315759 workType "article" @default.