FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2397342997> ?p ?o ?g. }

• W2397342997 endingPage "114" @default.
• W2397342997 startingPage "108" @default.
• W2397342997 abstract "The present study aimed to determine the associations between expressions of insulin-like growth factor-1 (IGF-1), tumor necrosis factor-α (TNF-α) and vascular endothelial growth factor 165 (VEGF165 ) in serum, and occurrence and development of type 2 diabetic nephropathy (DN).A total of 108 patients diagnosed as DN were randomly selected, including 50 patients in the microalbuminuria group, 44 patients in the macroalbuminuria group and 14 patients in the renal insufficiency group. Meanwhile, 97 healthy people were collected as a normal control group. Urinary albumin (UALB) and urine creatinine (Cr) of all participants were measured for 24 h, with their ratio (UALB/Cr) being calculated. Enzyme-linked immunosorbent assay was used to detect the serum concentrations of IGF-1, TNF-α and VEGF165 .The expressions of serum IGF-1, TNF-α and VEGF165 in the type 2 DN patients were significantly higher than those in the control group (all P < 0.05). The expressions of serum IGF-1, TNF-α and VEGF165 in the type 2 DN patients were positively correlated with UALB/Cr (all P < 0.05). As type 2 DN worsened, the expressions of serum IGF-1, TNF-α and VEGF165 increased, and type 2 DN severity had positive correlations with serum IGF-1, TNF-α and VEGF165 concentrations (all P < 0.05). There was a positive association between IGF-1 and TNF-α, IGF-1 and VEGF165 , and TNF-α and VEGF165 (all P < 0.05). Logistic regression analysis showed that IGF-1 and VEGF165 were associated with the progression of DN (both P < 0.05).Elevated expression levels of serum IGF-1, TNF-α and VEGF165 might exacerbate type 2 DN." @default.
• W2397342997 created "2016-06-24" @default.
• W2397342997 creator A5026071162 @default.
• W2397342997 creator A5045080979 @default.
• W2397342997 creator A5052421307 @default.
• W2397342997 creator A5081969615 @default.
• W2397342997 date "2016-07-15" @default.
• W2397342997 modified "2023-09-27" @default.
• W2397342997 title "Elevated expression levels of serum insulin-like growth factor-1, tumor necrosis factor-α and vascular endothelial growth factor 165 might exacerbate type 2 diabetic nephropathy" @default.
• W2397342997 cites W1481465818 @default.
• W2397342997 cites W159875719 @default.
• W2397342997 cites W193174988 @default.
• W2397342997 cites W1947673554 @default.
• W2397342997 cites W1967073098 @default.
• W2397342997 cites W1979726021 @default.
• W2397342997 cites W1981168254 @default.
• W2397342997 cites W1984253004 @default.
• W2397342997 cites W1984990263 @default.
• W2397342997 cites W1988201936 @default.
• W2397342997 cites W1988928503 @default.
• W2397342997 cites W1989197117 @default.
• W2397342997 cites W1996014308 @default.
• W2397342997 cites W2011396117 @default.
• W2397342997 cites W2016695234 @default.
• W2397342997 cites W2021585709 @default.
• W2397342997 cites W2028864226 @default.
• W2397342997 cites W2030128245 @default.
• W2397342997 cites W2031712296 @default.
• W2397342997 cites W2037759202 @default.
• W2397342997 cites W2041854617 @default.
• W2397342997 cites W2045159954 @default.
• W2397342997 cites W2052875048 @default.
• W2397342997 cites W2054020202 @default.
• W2397342997 cites W2120254272 @default.
• W2397342997 cites W2125401524 @default.
• W2397342997 cites W2127535781 @default.
• W2397342997 cites W2127944534 @default.
• W2397342997 cites W2128907843 @default.
• W2397342997 cites W2132130814 @default.
• W2397342997 cites W2133568993 @default.
• W2397342997 cites W2135113543 @default.
• W2397342997 cites W2136490577 @default.
• W2397342997 cites W2138699372 @default.
• W2397342997 cites W2170476872 @default.
• W2397342997 cites W2235544646 @default.
• W2397342997 cites W2393903490 @default.
• W2397342997 cites W2397342997 @default.
• W2397342997 cites W2409580004 @default.
• W2397342997 doi "https://doi.org/10.1111/jdi.12542" @default.
• W2397342997 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5217934" @default.
• W2397342997 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27218216" @default.
• W2397342997 hasPublicationYear "2016" @default.
• W2397342997 type Work @default.
• W2397342997 sameAs 2397342997 @default.
• W2397342997 citedByCount "28" @default.
• W2397342997 countsByYear W23973429972016 @default.
• W2397342997 countsByYear W23973429972017 @default.
• W2397342997 countsByYear W23973429972018 @default.
• W2397342997 countsByYear W23973429972019 @default.
• W2397342997 countsByYear W23973429972020 @default.
• W2397342997 countsByYear W23973429972021 @default.
• W2397342997 countsByYear W23973429972022 @default.
• W2397342997 countsByYear W23973429972023 @default.
• W2397342997 crossrefType "journal-article" @default.
• W2397342997 hasAuthorship W2397342997A5026071162 @default.
• W2397342997 hasAuthorship W2397342997A5045080979 @default.
• W2397342997 hasAuthorship W2397342997A5052421307 @default.
• W2397342997 hasAuthorship W2397342997A5081969615 @default.
• W2397342997 hasBestOaLocation W23973429971 @default.
• W2397342997 hasConcept C126322002 @default.
• W2397342997 hasConcept C134018914 @default.
• W2397342997 hasConcept C167734588 @default.
• W2397342997 hasConcept C170493617 @default.
• W2397342997 hasConcept C17991360 @default.
• W2397342997 hasConcept C2775960820 @default.
• W2397342997 hasConcept C2776174234 @default.
• W2397342997 hasConcept C2777025900 @default.
• W2397342997 hasConcept C2777180221 @default.
• W2397342997 hasConcept C2779922275 @default.
• W2397342997 hasConcept C2780306776 @default.
• W2397342997 hasConcept C2780689927 @default.
• W2397342997 hasConcept C2781184683 @default.
• W2397342997 hasConcept C2781203188 @default.
• W2397342997 hasConcept C555293320 @default.
• W2397342997 hasConcept C71924100 @default.
• W2397342997 hasConceptScore W2397342997C126322002 @default.
• W2397342997 hasConceptScore W2397342997C134018914 @default.
• W2397342997 hasConceptScore W2397342997C167734588 @default.
• W2397342997 hasConceptScore W2397342997C170493617 @default.
• W2397342997 hasConceptScore W2397342997C17991360 @default.
• W2397342997 hasConceptScore W2397342997C2775960820 @default.
• W2397342997 hasConceptScore W2397342997C2776174234 @default.
• W2397342997 hasConceptScore W2397342997C2777025900 @default.
• W2397342997 hasConceptScore W2397342997C2777180221 @default.
• W2397342997 hasConceptScore W2397342997C2779922275 @default.
• W2397342997 hasConceptScore W2397342997C2780306776 @default.
• W2397342997 hasConceptScore W2397342997C2780689927 @default.
• W2397342997 hasConceptScore W2397342997C2781184683 @default.

• next