FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2397372282> ?p ?o ?g. }

• W2397372282 endingPage "523" @default.
• W2397372282 startingPage "515" @default.
• W2397372282 abstract "BACKGROUND Airway hyperreactivity (AHR) has been described in patients with chronic obstructive pulmonary disease (COPD). However, the nature and characteristics of AHR in this disease have not been fully investigated. METHODS AHR was examined in a sample of 33 patients with COPD and 25 with asthma and compared during continuous inhalation of stepwise increased concentrations of methacholine. Respiratory resistance (Rrs) was measured by the forced oscillation technique and the dose-response curves were recorded. RESULTS The mean values for both forced vital capacity (FVC) and forced expiratory volume in 1s (FEV1) were well-preserved in subjects with asthma. In contrast, there was an obstructive ventilatory defect in patients with COPD, as evidenced by the FEV1/FVC ratio, which fell below 70%. Upon methacholine challenge, only 54.5% (18/33) of the patients with COPD had AHR, compared with 100% (25/25) of those with asthma. Analysis of the dose-response curves revealed that the patients with COPD had a significantly higher baseline Rrs, and thus lower baseline respiratory conductance (Grs), than those with asthma. The cumulative dose of methacholine capable of provoking a positive reaction was significantly higher in patients with COPD. The slope of the Grs was also less steep in responders with COPD. There was good correlation between the severity of AHR and the initial level of airway narrowing in patients with COPD (r=0.623, p<0.01), but not in those with asthma. CONCLUSION AHR is not uncommon in COPD, and it has different characteristics from that occurring in asthma." @default.
• W2397372282 created "2016-06-24" @default.
• W2397372282 creator A5059956590 @default.
• W2397372282 creator A5071843795 @default.
• W2397372282 date "2010-09-01" @default.
• W2397372282 modified "2023-09-28" @default.
• W2397372282 title "Comparison of airway hyperreactivity in chronic obstructive pulmonary disease and asthma." @default.
• W2397372282 cites W1974609791 @default.
• W2397372282 cites W1974714196 @default.
• W2397372282 cites W1980589975 @default.
• W2397372282 cites W2010556938 @default.
• W2397372282 cites W2011746431 @default.
• W2397372282 cites W2015689364 @default.
• W2397372282 cites W2039385416 @default.
• W2397372282 cites W2047136916 @default.
• W2397372282 cites W2047163318 @default.
• W2397372282 cites W2047699726 @default.
• W2397372282 cites W2072089748 @default.
• W2397372282 cites W2094203991 @default.
• W2397372282 cites W2101117478 @default.
• W2397372282 cites W2102252471 @default.
• W2397372282 cites W2106245415 @default.
• W2397372282 cites W2112649669 @default.
• W2397372282 cites W2116992584 @default.
• W2397372282 cites W2120593927 @default.
• W2397372282 cites W2123943059 @default.
• W2397372282 cites W2128955138 @default.
• W2397372282 cites W2134342786 @default.
• W2397372282 cites W2135414619 @default.
• W2397372282 cites W2159949995 @default.
• W2397372282 cites W2404325125 @default.
• W2397372282 cites W2404374861 @default.
• W2397372282 cites W2466998474 @default.
• W2397372282 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20979702" @default.
• W2397372282 hasPublicationYear "2010" @default.
• W2397372282 type Work @default.
• W2397372282 sameAs 2397372282 @default.
• W2397372282 citedByCount "8" @default.
• W2397372282 countsByYear W23973722822012 @default.
• W2397372282 countsByYear W23973722822013 @default.
• W2397372282 countsByYear W23973722822014 @default.
• W2397372282 countsByYear W23973722822020 @default.
• W2397372282 countsByYear W23973722822022 @default.
• W2397372282 crossrefType "journal-article" @default.
• W2397372282 hasAuthorship W2397372282A5059956590 @default.
• W2397372282 hasAuthorship W2397372282A5071843795 @default.
• W2397372282 hasConcept C105922876 @default.
• W2397372282 hasConcept C126322002 @default.
• W2397372282 hasConcept C164705383 @default.
• W2397372282 hasConcept C165637977 @default.
• W2397372282 hasConcept C2776042228 @default.
• W2397372282 hasConcept C2776178081 @default.
• W2397372282 hasConcept C2776780178 @default.
• W2397372282 hasConcept C2776954882 @default.
• W2397372282 hasConcept C2777714996 @default.
• W2397372282 hasConcept C2778333281 @default.
• W2397372282 hasConcept C2781260171 @default.
• W2397372282 hasConcept C3018587741 @default.
• W2397372282 hasConcept C42219234 @default.
• W2397372282 hasConcept C534529494 @default.
• W2397372282 hasConcept C55520419 @default.
• W2397372282 hasConcept C71924100 @default.
• W2397372282 hasConceptScore W2397372282C105922876 @default.
• W2397372282 hasConceptScore W2397372282C126322002 @default.
• W2397372282 hasConceptScore W2397372282C164705383 @default.
• W2397372282 hasConceptScore W2397372282C165637977 @default.
• W2397372282 hasConceptScore W2397372282C2776042228 @default.
• W2397372282 hasConceptScore W2397372282C2776178081 @default.
• W2397372282 hasConceptScore W2397372282C2776780178 @default.
• W2397372282 hasConceptScore W2397372282C2776954882 @default.
• W2397372282 hasConceptScore W2397372282C2777714996 @default.
• W2397372282 hasConceptScore W2397372282C2778333281 @default.
• W2397372282 hasConceptScore W2397372282C2781260171 @default.
• W2397372282 hasConceptScore W2397372282C3018587741 @default.
• W2397372282 hasConceptScore W2397372282C42219234 @default.
• W2397372282 hasConceptScore W2397372282C534529494 @default.
• W2397372282 hasConceptScore W2397372282C55520419 @default.
• W2397372282 hasConceptScore W2397372282C71924100 @default.
• W2397372282 hasIssue "5" @default.
• W2397372282 hasLocation W23973722821 @default.
• W2397372282 hasLocation W23973722822 @default.
• W2397372282 hasOpenAccess W2397372282 @default.
• W2397372282 hasPrimaryLocation W23973722821 @default.
• W2397372282 hasRelatedWork W1943988709 @default.
• W2397372282 hasRelatedWork W1984637839 @default.
• W2397372282 hasRelatedWork W1990265099 @default.
• W2397372282 hasRelatedWork W1992339557 @default.
• W2397372282 hasRelatedWork W1996251065 @default.
• W2397372282 hasRelatedWork W2004053857 @default.
• W2397372282 hasRelatedWork W2033715939 @default.
• W2397372282 hasRelatedWork W2069487184 @default.
• W2397372282 hasRelatedWork W2074674261 @default.
• W2397372282 hasRelatedWork W2078778309 @default.
• W2397372282 hasRelatedWork W2141133232 @default.
• W2397372282 hasRelatedWork W2371680903 @default.
• W2397372282 hasRelatedWork W2418874404 @default.
• W2397372282 hasRelatedWork W2490578505 @default.
• W2397372282 hasRelatedWork W2504618675 @default.

• next