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- W2397477825 abstract "Accumulating evidence suggests a role of inflammation in the pathophysiology of a number of neuropsychiatric diseases. The second generation antibiotic drug minocycline has potent neuroprotective and anti-inflammatory effects. We reported that minocycline could attenuate behavioral abnormalities and dopaminergic neurotoxicity in mice after administration of methamphetamine or 3,4-methylenedioxymethamphetamine (MDMA). Furthermore, we reported that minocycline was effective in the animal models of schizophrenia. Moreover, a double-blind, placebo-control, cross-over study showed that minocycline was effective in the rewarding effects in healthy human subjects. In this article, we would like to discuss minocycline as a potential therapeutic drug for methamphetamine-related disorders." @default.
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- W2397477825 date "2013-04-01" @default.
- W2397477825 modified "2023-09-28" @default.
- W2397477825 title "[Antibiotic drug minocycline: a potential therapeutic drug for methamphetamine-related disorders]." @default.
- W2397477825 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23808319" @default.
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