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• W2397588178 abstract "The rapid synthesis of peptides to support both exploratory peptide lead discovery and analog structure-activity studies has been the subject of intense research and technology development over the past few years (1– 4). Two general approaches have been advanced that may be classified as follows: (1) multiple peptide synthesis (MPS) and (2) combinatorial peptide synthesis (CPS). The peptide chemistry aspect of such multiple or combinatorial approaches typically integrates experimental methodologies that have been well established to date for the preparation of single peptides by solid-phase techniques. However, there exist novel and, in some cases, proprietary chemistry methods and/or materials that are essential to each of these approaches (vide infra). A common objective of the multiple or combinatorial approaches is to expedite the process and quantitative scope of synthetic peptide production in a manner that interfaces well with biological testing." @default.
• W2397588178 created "2016-06-24" @default.
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• W2397588178 date "2003-11-14" @default.
• W2397588178 modified "2023-09-27" @default.
• W2397588178 title "Multiple and Combinatorial Peptide Synthesis: Chemical Development and Biological Applications" @default.
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• W2397588178 doi "https://doi.org/10.1385/0-89603-274-4:305" @default.
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