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- W2397590185 abstract "We present a case report of Cogan's syndrome and a review of the literature. Cogan's syndrome, described in 1945, consists of nonsyphilitic interstitial keratitis accompanied by rapidly progressive bilateral hearing loss, tinnitus, and vertigo. 40% develop bilateral complete deafness and 70% show signs of systemic disease mostly in the form of cardiovascular symptoms. The mortality rate of 10% is mainly due to vasculitis. The disease is caused by an autoimmune response. One male patient had a typical interstitial keratitis and bilateral dramatically progressive deafness combined with failure of the vestibule. Corticosteroids and immunosuppressants are the treatment of choice. The importance of being aware of audiotory-vestibular dysfunction occurring in patients with ocular inflammation and the role of early immunotherapy in preventing deafness has to be emphasised." @default.
- W2397590185 created "2016-06-24" @default.
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- W2397590185 date "1998-08-26" @default.
- W2397590185 modified "2023-09-23" @default.
- W2397590185 title "[Cogan syndrome--a case report]." @default.
- W2397590185 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9782749" @default.
- W2397590185 hasPublicationYear "1998" @default.
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