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• W2397615757 endingPage "484" @default.
• W2397615757 startingPage "484" @default.
• W2397615757 abstract "Representing 2%-3% of adult cancers, renal cell carcinoma (RCC) accounts for 90% of renal malignancies and is the most lethal neoplasm of the urologic system. Over the last 65 years, the incidence of RCC has increased at a rate of 2% per year. The increased incidence is at least partly due to improved tumor detection secondary to greater availability of high-resolution cross-sectional imaging modalities over the last few decades. Most RCCs are asymptomatic at discovery and are detected as unexpected findings on imaging performed for unrelated clinical indications. The 2004 World Health Organization Classification of adult renal tumors stratifies RCC into several distinct histologic subtypes of which clear cell, papillary and chromophobe tumors account for 70%, 10%-15%, and 5%, respectively. Knowledge of the RCC subtype is important because the various subtypes are associated with different biologic behavior, prognosis and treatment options. Furthermore, the common RCC subtypes can often be discriminated non-invasively based on gross morphologic imaging appearances, signal intensity on T2-weighted magnetic resonance images, and the degree of tumor enhancement on dynamic contrast-enhanced computed tomography or magnetic resonance imaging examinations. In this article, we review the incidence and survival data, risk factors, clinical and biochemical findings, imaging findings, staging, differential diagnosis, management options and post-treatment follow-up of RCC, with attention focused on the common subtypes." @default.
• W2397615757 created "2016-06-24" @default.
• W2397615757 creator A5007541153 @default.
• W2397615757 creator A5047404548 @default.
• W2397615757 creator A5066558554 @default.
• W2397615757 creator A5069812419 @default.
• W2397615757 creator A5087518677 @default.
• W2397615757 date "2016-01-01" @default.
• W2397615757 modified "2023-10-03" @default.
• W2397615757 title "Review of renal cell carcinoma and its common subtypes in radiology" @default.
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