Matches in SemOpenAlex for { <https://semopenalex.org/work/W2397695087> ?p ?o ?g. }
- W2397695087 endingPage "802" @default.
- W2397695087 startingPage "789" @default.
- W2397695087 abstract "Introduction: Understanding the mechanism of DILI with MTA, and how to avoid and manage these toxicities is essential for minimising inferior cancer treatment outcomes. An organised and comprehensive overview of MTA-associated hepatotoxicity is lacking; this review aims to fill the gap.Areas covered: A literature review was performed based on published case reports and relevant studies or articles pertaining to the topics on PubMed. Food and Drug Administration drug information documents and search on the US National Library of Medicine LiverTox database was performed for all relevant MTA.Expert opinion: MTA-associated hepatotoxicity is common but rarely fatal. The pattern of hepatotoxicity is predominantly idiosyncratic. Pharmacogenomics show potential in predicting patients at risk of poorly metabolising or developing immunoallergic responses to MTA, but prospective data is scant. Preventing reactivation of viral hepatitis using anti-viral drugs, and avoidance of drug combinations at high risk of negative interactions are the most readily preventable measures for DILI." @default.
- W2397695087 created "2016-06-24" @default.
- W2397695087 creator A5001174272 @default.
- W2397695087 creator A5046498356 @default.
- W2397695087 date "2016-06-06" @default.
- W2397695087 modified "2023-09-26" @default.
- W2397695087 title "Hepatotoxicity of targeted therapy for cancer" @default.
- W2397695087 cites W1482302452 @default.
- W2397695087 cites W1484007224 @default.
- W2397695087 cites W1503340668 @default.
- W2397695087 cites W1509846886 @default.
- W2397695087 cites W1568927316 @default.
- W2397695087 cites W1592211817 @default.
- W2397695087 cites W1592992878 @default.
- W2397695087 cites W181042597 @default.
- W2397695087 cites W1927855523 @default.
- W2397695087 cites W1966723136 @default.
- W2397695087 cites W1967749640 @default.
- W2397695087 cites W1970955812 @default.
- W2397695087 cites W1973629782 @default.
- W2397695087 cites W1975182494 @default.
- W2397695087 cites W1975440270 @default.
- W2397695087 cites W1979235563 @default.
- W2397695087 cites W1981918114 @default.
- W2397695087 cites W1984855413 @default.
- W2397695087 cites W1985246288 @default.
- W2397695087 cites W1992253423 @default.
- W2397695087 cites W1994131804 @default.
- W2397695087 cites W1994202365 @default.
- W2397695087 cites W1996171607 @default.
- W2397695087 cites W1997234050 @default.
- W2397695087 cites W2004352153 @default.
- W2397695087 cites W2004564848 @default.
- W2397695087 cites W2007212814 @default.
- W2397695087 cites W2007276849 @default.
- W2397695087 cites W2015104488 @default.
- W2397695087 cites W2019121117 @default.
- W2397695087 cites W2023606875 @default.
- W2397695087 cites W2023952988 @default.
- W2397695087 cites W2028005470 @default.
- W2397695087 cites W2028713529 @default.
- W2397695087 cites W2031364396 @default.
- W2397695087 cites W2036082132 @default.
- W2397695087 cites W2042715023 @default.
- W2397695087 cites W2049887075 @default.
- W2397695087 cites W2059136273 @default.
- W2397695087 cites W2063136279 @default.
- W2397695087 cites W2063357192 @default.
- W2397695087 cites W2065902287 @default.
- W2397695087 cites W2069674339 @default.
- W2397695087 cites W2071002142 @default.
- W2397695087 cites W2071704606 @default.
- W2397695087 cites W2074557796 @default.
- W2397695087 cites W2077080958 @default.
- W2397695087 cites W2087931424 @default.
- W2397695087 cites W2087982142 @default.
- W2397695087 cites W2089707005 @default.
- W2397695087 cites W2090865105 @default.
- W2397695087 cites W2091312538 @default.
- W2397695087 cites W2091485274 @default.
- W2397695087 cites W2091945811 @default.
- W2397695087 cites W2097123674 @default.
- W2397695087 cites W2097474749 @default.
- W2397695087 cites W2098704420 @default.
- W2397695087 cites W2104425098 @default.
- W2397695087 cites W2105396478 @default.
- W2397695087 cites W2110466017 @default.
- W2397695087 cites W2111949444 @default.
- W2397695087 cites W2123029393 @default.
- W2397695087 cites W2124105609 @default.
- W2397695087 cites W2126314379 @default.
- W2397695087 cites W2129360604 @default.
- W2397695087 cites W2132157071 @default.
- W2397695087 cites W2132596236 @default.
- W2397695087 cites W2136202467 @default.
- W2397695087 cites W2138939215 @default.
- W2397695087 cites W2140620734 @default.
- W2397695087 cites W2142661339 @default.
- W2397695087 cites W2146404049 @default.
- W2397695087 cites W2148012276 @default.
- W2397695087 cites W2150946709 @default.
- W2397695087 cites W2151126163 @default.
- W2397695087 cites W2152405009 @default.
- W2397695087 cites W2158009793 @default.
- W2397695087 cites W2158801409 @default.
- W2397695087 cites W2163278353 @default.
- W2397695087 cites W2167123965 @default.
- W2397695087 cites W2167368130 @default.
- W2397695087 cites W2168467913 @default.
- W2397695087 cites W2171154436 @default.
- W2397695087 cites W2322536880 @default.
- W2397695087 cites W2323011677 @default.
- W2397695087 cites W2396314563 @default.
- W2397695087 cites W2590601395 @default.
- W2397695087 cites W4211124708 @default.
- W2397695087 doi "https://doi.org/10.1080/17425255.2016.1190831" @default.
- W2397695087 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27187715" @default.
- W2397695087 hasPublicationYear "2016" @default.