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- W2397935166 abstract "It was revealed in experiments on mice, that 3-hydroxypyridine derivatives possess marked anticonvulsive activity, especially in convulsions induced by GABA-ergic substances, less in corasol, maximal electroshock and strychnine induced ones. The anticonvulsive activity in the rows of 2-substituted and 2.6-disubstituted derivatives of 3-hydroxypyridine gets increased due to the introduction of larger in volume alkyl substitutes into the 2nd molecule position. Among the 2,6-disubstituted 3-hydroxypyridine derivatives, agents were revealed that are able to enhance hyperkinesis induced by 5-hydroxytryptophan." @default.
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- W2397935166 date "1986-11-01" @default.
- W2397935166 modified "2023-09-23" @default.
- W2397935166 title "[Relationship between the chemical structure and anticonvulsant activity of 3-hydroxypyridine derivatives]." @default.
- W2397935166 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3817140" @default.
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