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- W2398843503 abstract "The intrinsic and extrinsic factors that contribute to stem and neuronal precursor cell maintenance and/or differentiation remain poorly understood. Proteoglycans, major residents of the stem cell microenvironment, modulate key signaling cues and are of particular importance. We have taken a loss-of-function approach, by developing a library of bacterial lyases and sulfatases to specifically remodel the ECM and test the functional role of glycosaminoglycans (GAGs) in cell self-renewal, maintenance, and differentiation." @default.
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- W2398843503 date "2014-09-24" @default.
- W2398843503 modified "2023-09-23" @default.
- W2398843503 title "Mapping Proteoglycan Functions with Glycosidases" @default.
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- W2398843503 doi "https://doi.org/10.1007/978-1-4939-1714-3_34" @default.
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