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- W2398892015 abstract "As a result of the stimulation of beta-adrenostructures of the myocardium nonachlazin intensifies ino- and chronotropic functions of the heart. This effect does not manifest after administration of practolol and is less pronounced in animals anesthesized with urethane and alpha-chloralose since the sensitivity of the beta-adrenostructures of the myocardium decreases under the influence of the anesthetics. Apart from the stimulation of ino- and chronotropic function of the heart nonachlazin reduces concurrently the intensity of positive chronotropic effect of isoproterenol. Such a combination of the efects called a partial beta-adrenoblockade seems likely to play an important role in the manifestation of the antianginal action of nonachlazin." @default.
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- W2398892015 date "1980-09-01" @default.
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- W2398892015 title "[Effect of nonachlazine on ino- and chronotropic function]." @default.
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