FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2398985920> ?p ?o ?g. }

• W2398985920 abstract "ABSTRACT The urinary tract exits to a body surface area that is densely populated by a wide range of microbes. Yet, under most normal circumstances, it is typically considered sterile, i.e., devoid of microbes, a stark contrast to the gastrointestinal and upper respiratory tracts where many commensal and pathogenic microbes call home. Not surprisingly, infection of the urinary tract over a healthy person’s lifetime is relatively infrequent, occurring once or twice or not at all for most people. For those who do experience an initial infection, the great majority (70% to 80%) thankfully do not go on to suffer from multiple episodes. This is a far cry from the upper respiratory tract infections, which can afflict an otherwise healthy individual countless times. The fact that urinary tract infections are hard to elicit in experimental animals except with inoculum 3–5 orders of magnitude greater than the colony counts that define an acute urinary infection in humans (10 5 cfu/ml), also speaks to the robustness of the urinary tract defense. How can the urinary tract be so effective in fending off harmful microbes despite its orifice in a close vicinity to that of the microbe-laden gastrointestinal tract? While a complete picture is still evolving, the general consensus is that the anatomical and physiological integrity of the urinary tract is of paramount importance in maintaining a healthy urinary tract. When this integrity is breached, however, the urinary tract can be at a heightened risk or even recurrent episodes of microbial infections. In fact, recurrent urinary tract infections are a significant cause of morbidity and time lost from work and a major challenge to manage clinically. Additionally, infections of the upper urinary tract often require hospitalization and prolonged antibiotic therapy. In this chapter, we provide an overview of the basic anatomy and physiology of the urinary tract with an emphasis on their specific roles in host defense. We also highlight the important structural and functional abnormalities that predispose the urinary tract to microbial infections." @default.
• W2398985920 created "2016-06-24" @default.
• W2398985920 creator A5003048872 @default.
• W2398985920 creator A5005230681 @default.
• W2398985920 creator A5059105242 @default.
• W2398985920 date "2015-07-02" @default.
• W2398985920 modified "2023-09-25" @default.
• W2398985920 title "Anatomy and Physiology of the Urinary Tract: Relation to Host Defense and Microbial Infection" @default.
• W2398985920 cites W1520420475 @default.
• W2398985920 cites W1598421965 @default.
• W2398985920 cites W16033429 @default.
• W2398985920 cites W1604557362 @default.
• W2398985920 cites W167070833 @default.
• W2398985920 cites W1855103455 @default.
• W2398985920 cites W1895721865 @default.
• W2398985920 cites W1911301755 @default.
• W2398985920 cites W1964502738 @default.
• W2398985920 cites W1966050452 @default.
• W2398985920 cites W1966779040 @default.
• W2398985920 cites W1967255833 @default.
• W2398985920 cites W1968662302 @default.
• W2398985920 cites W1968860914 @default.
• W2398985920 cites W1969303917 @default.
• W2398985920 cites W1970012260 @default.
• W2398985920 cites W1975734972 @default.
• W2398985920 cites W1976499306 @default.
• W2398985920 cites W1979583290 @default.
• W2398985920 cites W1980273234 @default.
• W2398985920 cites W1983289453 @default.
• W2398985920 cites W1984360847 @default.
• W2398985920 cites W198934061 @default.
• W2398985920 cites W1989417284 @default.
• W2398985920 cites W1995025776 @default.
• W2398985920 cites W1996053208 @default.
• W2398985920 cites W1996128733 @default.
• W2398985920 cites W1998175274 @default.
• W2398985920 cites W1998933649 @default.
• W2398985920 cites W1999462217 @default.
• W2398985920 cites W2000694092 @default.
• W2398985920 cites W2001722972 @default.
• W2398985920 cites W2006003111 @default.
• W2398985920 cites W2008533115 @default.
• W2398985920 cites W2008969125 @default.
• W2398985920 cites W2011962188 @default.
• W2398985920 cites W2011978945 @default.
• W2398985920 cites W2013909710 @default.
• W2398985920 cites W2023956150 @default.
• W2398985920 cites W2024517620 @default.
• W2398985920 cites W2026396189 @default.
• W2398985920 cites W2026605505 @default.
• W2398985920 cites W2029719395 @default.
• W2398985920 cites W2030922755 @default.
• W2398985920 cites W2031084669 @default.
• W2398985920 cites W2033375782 @default.
• W2398985920 cites W2036912869 @default.
• W2398985920 cites W2037143694 @default.
• W2398985920 cites W2037706235 @default.
• W2398985920 cites W2039171179 @default.
• W2398985920 cites W2040853344 @default.
• W2398985920 cites W2042582341 @default.
• W2398985920 cites W2043924799 @default.
• W2398985920 cites W2046057509 @default.
• W2398985920 cites W2047387678 @default.
• W2398985920 cites W2047612713 @default.
• W2398985920 cites W2048439217 @default.
• W2398985920 cites W2049486312 @default.
• W2398985920 cites W2050608615 @default.
• W2398985920 cites W2052305034 @default.
• W2398985920 cites W2052967263 @default.
• W2398985920 cites W2053578611 @default.
• W2398985920 cites W2054157550 @default.
• W2398985920 cites W2054800529 @default.
• W2398985920 cites W2056517005 @default.
• W2398985920 cites W2057607176 @default.
• W2398985920 cites W2058605515 @default.
• W2398985920 cites W2060483617 @default.
• W2398985920 cites W2060494176 @default.
• W2398985920 cites W2061160238 @default.
• W2398985920 cites W2061314714 @default.
• W2398985920 cites W2062326841 @default.
• W2398985920 cites W2063044773 @default.
• W2398985920 cites W2068662457 @default.
• W2398985920 cites W2068778553 @default.
• W2398985920 cites W2072162069 @default.
• W2398985920 cites W2073589823 @default.
• W2398985920 cites W2075328063 @default.
• W2398985920 cites W2077185225 @default.
• W2398985920 cites W2079095590 @default.
• W2398985920 cites W2082802006 @default.
• W2398985920 cites W2083050091 @default.
• W2398985920 cites W2083718278 @default.
• W2398985920 cites W2084952061 @default.
• W2398985920 cites W2085615713 @default.
• W2398985920 cites W2085714969 @default.
• W2398985920 cites W2087285822 @default.
• W2398985920 cites W2088023172 @default.
• W2398985920 cites W2089541155 @default.
• W2398985920 cites W2091287519 @default.
• W2398985920 cites W2092603010 @default.
• W2398985920 cites W2093057533 @default.

• next