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• W2399093003 abstract "Lipid-derived inositol phosphates (InsPs) comprise a family of second messengers that arise through the action of six classes of InsP kinases, generally referred to as IPKs. Genetic studies have indicated that InsPs play critical roles in embryonic development, but the mechanisms of action for InsPs in mammalian cellular function are largely unknown. This chapter outlines a method for manipulating cellular InsP profiles through the coexpression of a constitutively active G protein and various IPKs. It provides a mechanism by which the metabolism of a variety of InsPs can be upregulated, enabling the evaluation of the effects of these InsPs on cellular functions." @default.
• W2399093003 created "2016-06-24" @default.
• W2399093003 creator A5054368544 @default.
• W2399093003 creator A5083015210 @default.
• W2399093003 date "2010-01-01" @default.
• W2399093003 modified "2023-09-23" @default.
• W2399093003 title "Molecular Manipulation and Analysis of Inositol Phosphate and Pyrophosphate Levels in Mammalian Cells" @default.
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• W2399093003 doi "https://doi.org/10.1007/978-1-60327-175-2_3" @default.
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