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- W2399219910 abstract "During acute progressive asphyxia an abrupt transition occurs from regular respiratory efforts to primary apnea and gasping. To study this transition we measured inspiratory duration (TI), expiratory duration (TE), maximal inspiratory tracheal pressure (Pmax), electromyographic activity (EMG) of different muscle groups, and the electrocorticogram (ECoG) of 3- to 5-day-old rabbits following airway occlusion at functional residual capacity (FRC). The onset of primary apnea was associated with other central nervous system events as indicated by decerebrate posture and maximal EMG activity which were followed by relaxation, loss of EMG activity, and an isoelectric ECoG. Indices of inspiratory drive (Pmax and Pmax/TI) were preserved or accentuated following primary apnea despite a reduction of overall respiratory activity (frequency X Pmax). The onset of primary apnea appears to be due to interruption of the respiratory cycling controls rather than failure of the respiratory center which regulates inspiratory force. Gasping appears to be linked with progressive changes in respiratory patterns which are observed prior to primary apnea. These findings do not support the concept of a gasping center." @default.
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- W2399219910 date "1977-09-01" @default.
- W2399219910 modified "2023-09-23" @default.
- W2399219910 title "Respiratory patterns during progressive asphyxia in newborn rabbits" @default.
- W2399219910 doi "https://doi.org/10.1152/jappl.1977.43.3.468" @default.
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