FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2399287961> ?p ?o ?g. }

• W2399287961 abstract "Some documented evidences proved small RNAs (sRNA) and targeted genes are involved in mammalian testicular development and spermatogenesis. However, the detailed molecular regulation mechanisms of them remain largely unknown so far. In this study, we obtained a total of 10,716 mRNAs, 67 miRNAs and 16,953 piRNAs which were differentially expressed between LC and LW pig breeds or between the two sexual maturity stages. Of which, we identified 16 miRNAs and 28 targeted genes possibly related to spermatogenesis; 14 miRNA and 18 targeted genes probably associated with cell adhesion related testis development. We also annotated 579 piRNAs which could potentially regulate cell death, nucleosome organization and other basic biology process, which implied that those piRNAs might be involved in sexual maturation difference. The integrated network analysis results suggested that some differentially expressed genes were involved in spermatogenesis through the ECM-receptor interaction, focal adhesion, Wnt and PI3K-Akt signaling pathways, some particular miRNAs have the negative regulation roles and some special piRNAs have the positive and negative regulation roles in testicular development. Our data provide novel insights into the molecular expression and regulation similarities and diversities of spermatogenesis and testicular development in different pig breeds at different stages of sexual maturity." @default.
• W2399287961 created "2016-06-24" @default.
• W2399287961 creator A5004066456 @default.
• W2399287961 creator A5044246694 @default.
• W2399287961 creator A5044315571 @default.
• W2399287961 creator A5046933385 @default.
• W2399287961 creator A5062371490 @default.
• W2399287961 creator A5067989213 @default.
• W2399287961 creator A5089205591 @default.
• W2399287961 creator A5090936274 @default.
• W2399287961 date "2016-05-27" @default.
• W2399287961 modified "2023-10-17" @default.
• W2399287961 title "Genome-wide differential expression of genes and small RNAs in testis of two different porcine breeds and at two different ages" @default.
• W2399287961 cites W1522985800 @default.
• W2399287961 cites W1551516145 @default.
• W2399287961 cites W1841553896 @default.
• W2399287961 cites W1952637467 @default.
• W2399287961 cites W1973839563 @default.
• W2399287961 cites W1973982821 @default.
• W2399287961 cites W1977733607 @default.
• W2399287961 cites W1977882976 @default.
• W2399287961 cites W1977911660 @default.
• W2399287961 cites W1978925194 @default.
• W2399287961 cites W1979815139 @default.
• W2399287961 cites W1980244456 @default.
• W2399287961 cites W1981501313 @default.
• W2399287961 cites W1982164922 @default.
• W2399287961 cites W1985221437 @default.
• W2399287961 cites W1985402847 @default.
• W2399287961 cites W1990040508 @default.
• W2399287961 cites W1992191734 @default.
• W2399287961 cites W1992848492 @default.
• W2399287961 cites W1995816084 @default.
• W2399287961 cites W1997499008 @default.
• W2399287961 cites W1997714925 @default.
• W2399287961 cites W1998297488 @default.
• W2399287961 cites W2004271888 @default.
• W2399287961 cites W2004616940 @default.
• W2399287961 cites W2006246049 @default.
• W2399287961 cites W2011612823 @default.
• W2399287961 cites W2015694530 @default.
• W2399287961 cites W2021217098 @default.
• W2399287961 cites W2022346384 @default.
• W2399287961 cites W2022531748 @default.
• W2399287961 cites W2024159010 @default.
• W2399287961 cites W2026222098 @default.
• W2399287961 cites W2030406469 @default.
• W2399287961 cites W2030755826 @default.
• W2399287961 cites W2038308632 @default.
• W2399287961 cites W2038514859 @default.
• W2399287961 cites W2041509376 @default.
• W2399287961 cites W2043312094 @default.
• W2399287961 cites W2043702892 @default.
• W2399287961 cites W2044545834 @default.
• W2399287961 cites W2046919826 @default.
• W2399287961 cites W2047649140 @default.
• W2399287961 cites W2051708324 @default.
• W2399287961 cites W2053834034 @default.
• W2399287961 cites W2056993481 @default.
• W2399287961 cites W2058558482 @default.
• W2399287961 cites W2061449432 @default.
• W2399287961 cites W2062547614 @default.
• W2399287961 cites W2063687663 @default.
• W2399287961 cites W2066118199 @default.
• W2399287961 cites W2068274700 @default.
• W2399287961 cites W2069605178 @default.
• W2399287961 cites W2070053574 @default.
• W2399287961 cites W2076970941 @default.
• W2399287961 cites W2085077505 @default.
• W2399287961 cites W2091339627 @default.
• W2399287961 cites W2092723228 @default.
• W2399287961 cites W2096196036 @default.
• W2399287961 cites W2103012554 @default.
• W2399287961 cites W2103028411 @default.
• W2399287961 cites W2105044592 @default.
• W2399287961 cites W2106084493 @default.
• W2399287961 cites W2106235822 @default.
• W2399287961 cites W2109556804 @default.
• W2399287961 cites W2112363802 @default.
• W2399287961 cites W2114104545 @default.
• W2399287961 cites W2117391818 @default.
• W2399287961 cites W2123551357 @default.
• W2399287961 cites W2132713636 @default.
• W2399287961 cites W2133465414 @default.
• W2399287961 cites W2133948311 @default.
• W2399287961 cites W2137916429 @default.
• W2399287961 cites W2138242620 @default.
• W2399287961 cites W2138626530 @default.
• W2399287961 cites W2140694202 @default.
• W2399287961 cites W2142767404 @default.
• W2399287961 cites W2144064755 @default.
• W2399287961 cites W2147495091 @default.
• W2399287961 cites W2148105495 @default.
• W2399287961 cites W2151126975 @default.
• W2399287961 cites W2151995214 @default.
• W2399287961 cites W2152026276 @default.
• W2399287961 cites W2159559543 @default.
• W2399287961 cites W2159675211 @default.
• W2399287961 cites W2161222316 @default.
• W2399287961 cites W2162674813 @default.

• next