Matches in SemOpenAlex for { <https://semopenalex.org/work/W2399583093> ?p ?o ?g. }
Showing items 1 to 64 of
64
with 100 items per page.
- W2399583093 endingPage "44" @default.
- W2399583093 startingPage "37" @default.
- W2399583093 abstract "In nuclear medicine, the search for the perfect hepatobiliary agent started in 1955 with the rose bengal dye labeled with 131I. With the advent of technetium-99m, many ligands were labeled and Tc-99m-PG and 99mTc-HIDA were among the best suited for this purpose. Both were synthesized at the radiopharmacy laboratory during 1977-1980 and have been used at INNSZ for clinical studies. For the last three years, a new ligand with a bromine atom and an extra methyl radical has been reported as being one of the best third generation HIDAs. We received the gift of several kits of trimethyl-Br-IDA from Sorin Biomedica, Italy, (A) and of Mebrofenin from ININ, Mexico, (B) to be labeled and tested in order to select one of them for clinical work. For a comparative study on the radiopharmacodynamic characteristics of the two labeled ligands, six healthy women volunteered to undergo two tests with a 72 hour hour rest period to assure complete washout. After the I.V. dose of 111 MBq (3 mCi) the dynamic study was started and a total of 127 16-second images were acquired with a Siemens Digitrac 750 scintillation camera coupled to a Scintiview computer. Static images were taken at the end of the dynamic study and after breakfast. Blood and urine samples were collected for 24 hours and the amount of radioactivity was measured with a well type scintillation detector. The radiopharmacokinetic results are listed in tables 1-4.(ABSTRACT TRUNCATED AT 250 WORDS)" @default.
- W2399583093 created "2016-06-24" @default.
- W2399583093 creator A5007051919 @default.
- W2399583093 creator A5012693036 @default.
- W2399583093 creator A5014684551 @default.
- W2399583093 creator A5042232943 @default.
- W2399583093 creator A5061348548 @default.
- W2399583093 creator A5076025046 @default.
- W2399583093 creator A5076524672 @default.
- W2399583093 creator A5089503487 @default.
- W2399583093 date "1989-01-01" @default.
- W2399583093 modified "2023-09-27" @default.
- W2399583093 title "The pharmacokinetic characteristics of a hepatobiliary 99mTc-radiopharmaceutical: comparison of the imported and national kits." @default.
- W2399583093 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2727431" @default.
- W2399583093 hasPublicationYear "1989" @default.
- W2399583093 type Work @default.
- W2399583093 sameAs 2399583093 @default.
- W2399583093 citedByCount "0" @default.
- W2399583093 crossrefType "journal-article" @default.
- W2399583093 hasAuthorship W2399583093A5007051919 @default.
- W2399583093 hasAuthorship W2399583093A5012693036 @default.
- W2399583093 hasAuthorship W2399583093A5014684551 @default.
- W2399583093 hasAuthorship W2399583093A5042232943 @default.
- W2399583093 hasAuthorship W2399583093A5061348548 @default.
- W2399583093 hasAuthorship W2399583093A5076025046 @default.
- W2399583093 hasAuthorship W2399583093A5076524672 @default.
- W2399583093 hasAuthorship W2399583093A5089503487 @default.
- W2399583093 hasConcept C126322002 @default.
- W2399583093 hasConcept C177322064 @default.
- W2399583093 hasConcept C185592680 @default.
- W2399583093 hasConcept C2780026642 @default.
- W2399583093 hasConcept C2989005 @default.
- W2399583093 hasConcept C522557706 @default.
- W2399583093 hasConcept C71839028 @default.
- W2399583093 hasConcept C71924100 @default.
- W2399583093 hasConceptScore W2399583093C126322002 @default.
- W2399583093 hasConceptScore W2399583093C177322064 @default.
- W2399583093 hasConceptScore W2399583093C185592680 @default.
- W2399583093 hasConceptScore W2399583093C2780026642 @default.
- W2399583093 hasConceptScore W2399583093C2989005 @default.
- W2399583093 hasConceptScore W2399583093C522557706 @default.
- W2399583093 hasConceptScore W2399583093C71839028 @default.
- W2399583093 hasConceptScore W2399583093C71924100 @default.
- W2399583093 hasIssue "1" @default.
- W2399583093 hasLocation W23995830931 @default.
- W2399583093 hasOpenAccess W2399583093 @default.
- W2399583093 hasPrimaryLocation W23995830931 @default.
- W2399583093 hasRelatedWork W1582319023 @default.
- W2399583093 hasRelatedWork W1964027243 @default.
- W2399583093 hasRelatedWork W2018102644 @default.
- W2399583093 hasRelatedWork W2042484752 @default.
- W2399583093 hasRelatedWork W2061878662 @default.
- W2399583093 hasRelatedWork W2082303032 @default.
- W2399583093 hasRelatedWork W209499230 @default.
- W2399583093 hasRelatedWork W233649044 @default.
- W2399583093 hasRelatedWork W2380539982 @default.
- W2399583093 hasRelatedWork W2417855701 @default.
- W2399583093 hasVolume "41" @default.
- W2399583093 isParatext "false" @default.
- W2399583093 isRetracted "false" @default.
- W2399583093 magId "2399583093" @default.
- W2399583093 workType "article" @default.