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- W2399682834 abstract "Stable human leukemia-lymphoma cell lines provide model systems to study the processes involved in leukemic and normal cell differentiation [10]. Leukemic cells, arrested at a certain stage of differentiation, can be triggered to differentiate to functionally and morphologically more mature cells [7]. Both “fresh” leukemic cells and cells maintained in long-term culture are sensitive to in vitro induction of differentiation. Furthermore, cell differentiation is a novel concept in the treatment of acute leukemias and several substances such as low dose Ara-C and the physiologic Compound retinoic acid have been shown to act as differentiating agents in vivo [7].KeywordsAcute LeukemiaErythroleukemia Cell LineCarboxylic EsteraseMyelogenous Leukemia Cell LineHuman Erythroleukemia Cell LineThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves." @default.
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- W2399682834 date "1985-01-01" @default.
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- W2399682834 title "Changes in Isoenzyme Patterns Expressed by the Erythroleukemia Cell Lines K-562 and HEL After Induction of Differentiation" @default.
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- W2399682834 doi "https://doi.org/10.1007/978-3-642-70385-0_88" @default.
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