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- W2399692545 abstract "A number of radioactive steroid and sterol compounds were infused into the human term placenta in situ in an effort to assess their potential as precursors for progesterone production. Pregnenolone and pregnenolone sulfate were most efficiently converted to progesterone (12.8 and 12.9 per cent of injected radioactive material). 20β-dihydroprogesterone, 20β-dihydropregnenolone, and 20β-dihydropregnenolone-3-sulfate were converted in very low yield (<0.1 per cent). No radioactive progesterone was isolated after infusion with cholesterol, cholesterol sulfate, or 20α-dihydroprogesterone sulfate." @default.
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- W2399692545 date "1969-01-01" @default.
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- W2399692545 title "Utilization of precursor steroids in placental progesterone**The trivial names used throughout this paper are: progesterone=preg-4-ene-3, 20-dione; pregnenolone=3β-hydroxy-pregn-5-en-20-one; cholesterol=cholest-5-en-3β-ol; 20α-dihydroprogesterone=20α-hydroxy-pregn-4-en-3-one; 20β-dihydroprogesterone=20β-hydroxy-pregn-4-en-3-one; 20β-dihydropregnenolone=pregn-5-ene-3β, 20β-diol; 20α-dihydropregnenolone=pregn-5-ene-3β, 20a-diol; pregnenolone sulfate=pregn-5-ene-3β-yl sulfate; cholesterol sulfate=…" @default.
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- W2399692545 doi "https://doi.org/10.1016/s0002-9378(16)34339-3" @default.
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