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- W2399693630 abstract "There is only one antigen specifically associated with the hepatitis delta virus (HDV) infection, i.e., the hepatitis delta antigen (HDAg) (1,2). HDAg is a phosphoprotein encoded by an open reading frame conserved among all HDV isolates. HDAg is a structural protein, because approx 200 subunits of HDAg bind via specific domains to genomic RNA, forming a core-like structure within an envelope provided by the co-infecting helper hepadnavirus (3). HDAg consists of two protein species of 24 kDa (195 amino acids) and 27 kDa (214 amino acids), referred to as small HDAg (S-HDAg) and large HDAg (L-HDAg), respectively. Those two proteins share the same primary structure, except for a unique 19-amino-acid sequence found at the C-terminus of L-HDAg, which possesses packaging activity. This additional sequence found in L-HDAg is synthesized via an RNA-editing process during HDV replication." @default.
- W2399693630 created "2016-06-24" @default.
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- W2399693630 date "2004-02-04" @default.
- W2399693630 modified "2023-09-26" @default.
- W2399693630 title "Immunohistochemical Detection of Hepatitis Delta Antigen" @default.
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- W2399693630 doi "https://doi.org/10.1385/1-59259-669-x:107" @default.
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