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• W2399849987 startingPage "757" @default.
• W2399849987 abstract "beta-Endorphin has a role in the regulation of the normal menstrual cycle and possibly in the onset of puberty. We have reviewed the evidence pointing to an alteration in this neuropeptide that may contribute to the pathogenesis of various reproductive dysfunctions. Elevated or high levels of beta-endorphin have been associated with exercise-associated amenorrhea, stress-associated amenorrhea, and polycystic ovarian syndrome. Depressed or low levels of beta-endorphin have been associated with PMS and menopause. Alterations in the levels of beta-endorphin may change the pulsatile release of GnRH via noradrenergic and/or dopaminergic pathways. We have primarily focused on beta-endorphin as representative of the endogenous opioid peptides, but other opioid peptides may also contribute to the pathogenesis of various types of reproductive dysfunction. Perhaps it will become possible to characterize and hone our understanding of the function of beta-endorphin and the other substances composing the endogenous opioid peptides. A better understanding of their role in physiological as well as pathophysiological processes may allow for the development of rational approaches to the treatment of specific disorders pertaining to reproduction. Many questions remain unanswered. Among the most relevant are: what is the precise mechanism of action by which beta-endorphin exerts its influence on pulsatile GnRH release? Is there a functional relationship between CNS and peripheral (serum) levels of beta-endorphin? Are the detected changes in beta-endorphin levels merely associated, or are they a cause of a particular disorder? Since it took almost 40 years between the time prostaglandins were first discovered and eventual realization of their clinical application, it may take some time before the beta-endorphin story is complete." @default.
• W2399849987 created "2016-06-24" @default.
• W2399849987 creator A5081583405 @default.
• W2399849987 creator A5090600683 @default.
• W2399849987 date "1990-11-01" @default.
• W2399849987 modified "2023-09-26" @default.
• W2399849987 title "Current concepts of β-endorphin physiology in female reproductive dysfunction" @default.
• W2399849987 cites W115044221 @default.
• W2399849987 cites W1516113332 @default.
• W2399849987 cites W1605089600 @default.
• W2399849987 cites W165233755 @default.
• W2399849987 cites W17879684 @default.
• W2399849987 cites W1813350052 @default.
• W2399849987 cites W188895391 @default.
• W2399849987 cites W194639418 @default.
• W2399849987 cites W1953761948 @default.
• W2399849987 cites W1965036886 @default.
• W2399849987 cites W1965584350 @default.
• W2399849987 cites W1967497954 @default.
• W2399849987 cites W1968003395 @default.
• W2399849987 cites W1969214528 @default.
• W2399849987 cites W1970956274 @default.
• W2399849987 cites W1971127281 @default.
• W2399849987 cites W1972181075 @default.
• W2399849987 cites W1972836142 @default.
• W2399849987 cites W1974294738 @default.
• W2399849987 cites W1974400581 @default.
• W2399849987 cites W1975832789 @default.
• W2399849987 cites W1976030186 @default.
• W2399849987 cites W1976362125 @default.
• W2399849987 cites W1977493234 @default.
• W2399849987 cites W1978086274 @default.
• W2399849987 cites W1978589358 @default.
• W2399849987 cites W1978643341 @default.
• W2399849987 cites W1979122053 @default.
• W2399849987 cites W1979470000 @default.
• W2399849987 cites W1980105020 @default.
• W2399849987 cites W1980288970 @default.
• W2399849987 cites W1980636216 @default.
• W2399849987 cites W1982630707 @default.
• W2399849987 cites W1984345962 @default.
• W2399849987 cites W1984389220 @default.
• W2399849987 cites W1985932306 @default.
• W2399849987 cites W1989252539 @default.
• W2399849987 cites W1992466834 @default.
• W2399849987 cites W1993414262 @default.
• W2399849987 cites W1995339389 @default.
• W2399849987 cites W1996694042 @default.
• W2399849987 cites W1998987940 @default.
• W2399849987 cites W2000470884 @default.
• W2399849987 cites W2000592319 @default.
• W2399849987 cites W2001625528 @default.
• W2399849987 cites W2003020292 @default.
• W2399849987 cites W2005911490 @default.
• W2399849987 cites W2008996373 @default.
• W2399849987 cites W2010051841 @default.
• W2399849987 cites W2013443396 @default.
• W2399849987 cites W2014380747 @default.
• W2399849987 cites W2014703688 @default.
• W2399849987 cites W2015101172 @default.
• W2399849987 cites W2015384542 @default.
• W2399849987 cites W2015898953 @default.
• W2399849987 cites W2016142562 @default.
• W2399849987 cites W2016768533 @default.
• W2399849987 cites W2017214509 @default.
• W2399849987 cites W2019524797 @default.
• W2399849987 cites W2020865843 @default.
• W2399849987 cites W2022955668 @default.
• W2399849987 cites W2024248007 @default.
• W2399849987 cites W2024968806 @default.
• W2399849987 cites W2025372252 @default.
• W2399849987 cites W2028502151 @default.
• W2399849987 cites W2029995932 @default.
• W2399849987 cites W2032964943 @default.
• W2399849987 cites W2032997748 @default.
• W2399849987 cites W2033680879 @default.
• W2399849987 cites W2036940525 @default.
• W2399849987 cites W2039065113 @default.
• W2399849987 cites W2039829070 @default.
• W2399849987 cites W2041445767 @default.
• W2399849987 cites W2043979707 @default.
• W2399849987 cites W2044985824 @default.
• W2399849987 cites W2046662261 @default.
• W2399849987 cites W2047559243 @default.
• W2399849987 cites W2057406853 @default.
• W2399849987 cites W2058749969 @default.
• W2399849987 cites W2059392094 @default.
• W2399849987 cites W2059792931 @default.
• W2399849987 cites W2060367584 @default.
• W2399849987 cites W2060417855 @default.
• W2399849987 cites W2062451992 @default.
• W2399849987 cites W2063159601 @default.
• W2399849987 cites W2064288087 @default.
• W2399849987 cites W2066049272 @default.
• W2399849987 cites W2068948430 @default.
• W2399849987 cites W2074488082 @default.
• W2399849987 cites W2075011388 @default.
• W2399849987 cites W2075856101 @default.

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